Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development
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DOI: 10.1371/journal.pgen.1010765
Abstract: An essential process during Danio rerio’s left-right organizer (Kupffer’s Vesicle, KV) development is for the majority of developing KV cells to form a motile cilium that extend into the KV lumen. Left-right beating of motile… read more here.
Keywords: development; cilia formation; rab8 rab11; formation ... See more keywords
Abnormal left-right organizer and laterality defects in Xenopus embryos after formin inhibitor SMIFH2 treatment
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DOI: 10.1371/journal.pone.0275164
Abstract: Left-right symmetry breaking in most studied vertebrates makes use of so-called leftward flow, a mechanism which was studied in detail especially in mouse and Xenopus laevis embryos and is based on rotation of monocilia on… read more here.
Keywords: organizer laterality; left right; treatment; right organizer ... See more keywords
Understanding laterality disorders and the left-right organizer: Insights from zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1035513
Abstract: Vital internal organs display a left-right (LR) asymmetric arrangement that is established during embryonic development. Disruption of this LR asymmetry—or laterality—can result in congenital organ malformations. Situs inversus totalis (SIT) is a complete concordant reversal… read more here.
Keywords: development; laterality; laterality disorders; left right ... See more keywords