Biolayer Interferometry-based FcγRIIa binding assay for a therapeutic antibody with strong effector function.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113842
Abstract: FcγRIIa receptor binding is part of the mechanism of action for many therapeutic antibodies. AlphaScreen® technology and Biolayer Interferometry (BLI) are often used to assess protein-protein interactions. Recently we demonstrated that the presence of aggregates… read more here.
Keywords: based riia; riia; binding assay; biolayer interferometry ... See more keywords
The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease
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DOI: 10.18632/oncotarget.13489
Abstract: Previous research has found patients with the FcγRIIIB NA1 variant having increased risk of intravenous immunoglobulin (IVIG) resistance in Kawasaki disease (KD). Our previous studies revealed that elevated FcγRIIA expression correlated with the susceptibility of… read more here.
Keywords: riia; treatment; formation; expression ... See more keywords