CLEC18A Impairs Phagocytosis by Reducing FcγRIIA Expression and Arresting Autophagosome-Lysosome Fusion
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DOI: 10.1128/spectrum.02903-22
Abstract: During infection, the host immune system produces cellular factors to protect against pathogen invasion. However, when the immune response overreacts and there is dysregulated cytokine homeostasis, autoimmunity occurs following an infection. ABSTRACT Mixed cryoglobulinemia (MC)… read more here.
Keywords: lysosome fusion; autophagosome lysosome; infection; riia expression ... See more keywords