A tumor-promoting role for soluble TβRIII in glioblastoma
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-021-04128-y
Abstract: Purpose Members of the transforming growth factor (TGF)-β superfamily play a key role in the regulation of the malignant phenotype of glioblastoma by promoting invasiveness, angiogenesis, immunosuppression, and maintaining stem cell-like properties. Betaglycan, a TGF-β… read more here.
Keywords: riii; glioblastoma; role; soluble riii ... See more keywords
TβRIII is induced by TCR signaling and downregulated in FoxP3+ regulatory T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.10.081
Abstract: TGF-β type III receptor (TβRIII) is a co-receptor for TGFβ family members required for high-affinity binding of these ligands to their receptors, potentiating their cellular functions. TGF-βs, Bone Morphogenetic Proteins (BMP2/4) and Inhibins/Activins regulate different… read more here.
Keywords: cells riii; riii; riii induced; induced tcr ... See more keywords
The Fab portion of immunoglobulin G has sites in the CL domain that interact with Fc gamma receptor IIIa
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2038531
Abstract: ABSTRACT The interaction between IgG and Fc gamma receptor IIIa (FcγRIIIa) is essential for mediating immune responses. Recent studies have shown that the antigen binding fragment (Fab) and Fc are involved in IgG-FcγRIII interactions. Here,… read more here.
Keywords: interaction; igg riii; riii; gamma receptor ... See more keywords
Up‐regulation of TβRIII facilitates the osteogenesis of supraspinous ligament‐derived fibroblasts from patients with ankylosing spondylitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16262
Abstract: Spinal supraspinous ligament (SL) osteogenesis is the key risk of ankylosing spondylitis (AS), with an unclear pathogenesis. We previously found that transforming growth factor β1 (TGF‐β1), bone morphogenetic proteins (eg BMP2) and type III TGF‐β1… read more here.
Keywords: supraspinous ligament; riii; ankylosing spondylitis; bmp2 ... See more keywords
Plasma levels and tissue expression of soluble TGFβrIII receptor in women with early-stage breast cancer and in healthy women: a prospective observational study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-020-02659-4
Abstract: Background Mammary carcinogenesis is partly regulated by the transforming growth factor beta (TGFβ) signaling pathway. Its function in cancer progression and metastasis is highly dependent on disease stage, and it is likely modulated by the… read more here.
Keywords: plasma; riii; stgf riii; breast cancer ... See more keywords
Transforming growth factor receptor III (Betaglycan) regulates the generation of pathogenic Th17 cells in EAE
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1088039
Abstract: The transforming growth factor receptor III (TβRIII) is commonly recognized as a co-receptor that promotes the binding of TGFβ family ligands to type I and type II receptors. Within the immune system, TβRIII regulates T… read more here.
Keywords: riii; th17; mice; receptor ... See more keywords