Tractable Method for Rapid Quality Assessment of Therapeutic Antibodies in Harvested Cell Culture Fluid based on FcγRIIIa-Immobilized Magnetic Microspheres.
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DOI: 10.1021/acs.analchem.2c01350
Abstract: FcγRIIIa-binding affinity is one of the key factors to ensure the efficacy of many antitumor therapeutic antibodies, which should be monitored along with the titer, protein aggregation, and other critical quality attributes. The conventional workflow… read more here.
Keywords: therapeutic antibodies; quality; quality assessment; riiia immobilized ... See more keywords