Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children
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DOI: 10.1186/s12936-021-03901-0
Abstract: Background The FcγRs genotypes have been reported to play a key role in the defence against malaria parasites through both cellular and humoral immunity. This study aimed to investigate the possible correlation between FcγR (… read more here.
Keywords: malaria; anti malarial; riiib; genes polymorphism ... See more keywords
The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils
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DOI: 10.3389/fimmu.2021.657393
Abstract: Human neutrophils express two unique antibody receptors for IgG, the FcγRIIa and the FcγRIIIb. FcγRIIa contains an immunoreceptor tyrosine-based activation motif (ITAM) sequence within its cytoplasmic tail, which is important for initiating signaling. In contrast,… read more here.
Keywords: calcium rise; riiib; calcium; human neutrophils ... See more keywords