FYCO1 mediates clearance of α‐synuclein aggregates through a Rab7‐dependent mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14461
Abstract: Parkinson's disease can be caused by mutations in the α‐synuclein gene and is characterized by aggregates of α‐synuclein protein. We have previously shown that over‐expression of the small GTPase Rab7 can induce clearance of α‐synuclein… read more here.
Keywords: synuclein; synuclein aggregates; fyco1; clearance ... See more keywords
The role of microtubules and the dynein/dynactin motor complex of host cells in the biogenesis of the Coxiella burnetii-containing vacuole
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DOI: 10.1371/journal.pone.0209820
Abstract: Microtubules (Mts) are dynamic cytoskeleton structures that play a key role in vesicular transport. The Mts-mediated transport depends on motor proteins named kinesins and the dynein/dynactin motor complex. The Rab7 adapter protein FYCO1 controls the… read more here.
Keywords: dynein dynactin; ccv; transport; role ... See more keywords