Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog
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DOI: 10.1038/s41598-018-26444-y
Abstract: Sodium channel inhibitor drugs decrease pathological hyperactivity in various diseases including pain syndromes, myotonia, arrhythmias, nerve injuries and epilepsies. Inhibiting pathological but not physiological activity, however, is a major challenge in drug development. Sodium channel… read more here.
Keywords: modulation; non blocking; riluzole analog; sodium channel ... See more keywords