Paramagnetic Rim Lesions are Specific to Multiple Sclerosis: An International Multicenter 3T MRI Study
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DOI: 10.1002/ana.25877
Abstract: In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports their association with severity of clinical disease. We studied… read more here.
Keywords: multicenter; paramagnetic rim; multiple sclerosis; international multicenter ... See more keywords
What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2022.2143265
Abstract: ABSTRACT Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a subset of chronic active lesions (CALs), which have been linked through clinical and pathological studies to more severe disease course and… read more here.
Keywords: potential paramagnetic; lesions diagnostic; rim lesions; multiple sclerosis ... See more keywords
Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions
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DOI: 10.1093/brain/awy296
Abstract: Chronic active multiple sclerosis lesions, characterized by a hyperintense rim of iron-enriched, activated microglia and macrophages, have been linked to greater tissue damage. Post-mortem studies have determined that chronic active lesions are primarily related to… read more here.
Keywords: susceptibility; susceptibility mapping; multiple sclerosis; rim lesions ... See more keywords
Quantitative susceptibility mapping versus phase imaging to identify multiple sclerosis iron rim lesions with demyelination
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DOI: 10.1111/jon.12987
Abstract: To compare quantitative susceptibility mapping (QSM) and high‐pass‐filtered (HPF) phase imaging for (1) identifying chronic active rim lesions with more myelin damage and (2) distinguishing patients with increased clinical disability in multiple sclerosis. read more here.
Keywords: susceptibility mapping; phase imaging; rim lesions; multiple sclerosis ... See more keywords