Streptozotocin produces oxidative stress, inflammation and decreases BDNF concentrations to induce apoptosis of RIN5F cells and type 2 diabetes mellitus in Wistar rats.
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DOI: 10.1016/j.bbrc.2017.03.054
Abstract: BACKGROUND Neurodegenerative disorders, such as deficits in learning, memory and cognition and Alzheimer's disease are associated with diabetes mellitus. Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor and is known to possess anti-obesity, anti-diabetic actions… read more here.
Keywords: stz; diabetes mellitus; rin5f cells; rin5f ... See more keywords