Annulation of pyrrole ring in 4-acylpyridine-3,5-dicarbonitriles in the presence of ammonia
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DOI: 10.1007/s10593-019-02434-4
Abstract: 4-Acyl-2-amino-6-chloropyridine-3,5-dicarbonitriles underwent heterocyclization in the presence of ammonia in aqueous dioxane medium, involving the ortho-ketonitrile fragment while preserving the halogen atom. The pyrrole ring annulation process proceeded regioselectively with the formation of a single positional… read more here.
Keywords: pyrrole ring; annulation pyrrole; acylpyridine dicarbonitriles; ring acylpyridine ... See more keywords