Synthesis of Benzothiazolopyrimidine Diastereomers Through a Copper‐Catalyzed Azide–Alkyne Cycloaddition/Ring‐Cleavage/[4 + 2] Cycloaddition Sequence
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202500714
Abstract: Copper‐catalyzed reactions of 2‐benzothiazolimines, terminal ynones, and sulfonyl azides afforded benzothiazolopyrimidine diastereomers. The transformation involved a tandem CuAAC/ring‐cleavage/[4 + 2] cycloaddition procedure with one‐pot synthesis under mild conditions. The benzothiazolopyrimidine diastereomers could be isolated, and their structure… read more here.
Keywords: ring cleavage; copper catalyzed; benzothiazolopyrimidine diastereomers; cycloaddition ... See more keywords
Metagenomic analysis of aromatic ring-cleavage mechanism in nano-Fe3O4@activated coke enhanced bio-system for coal pyrolysis wastewater treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2021.125387
Abstract: In current study, nano-Fe3O4@activated coke enhanced bio-system (FEBS) under limited-oxygen condition was applied for efficient treatment of aromatic organics in coal pyrolysis wastewater. Metagenomic analyses revealed functional microbiome linkages and mechanism involved in aromatic ring-cleavage.… read more here.
Keywords: nano fe3o4; cleavage; analysis; ring cleavage ... See more keywords
Synthesis of 1-(2-bromo-1-arylethyl)-1H-benzotriazoles via NBS promoted addition of 1H-benzotriazole to alkene: Relevance in benzotriazole ring cleavage
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131078
Abstract: Abstract A cost-effective and expeditious one-pot synthesis of 1-(2-bromo-1-arylethyl)-1H-benzotriazoles has been devised by reacting styrene and their derivatives with 1H-benzotriazole in presence of N-bromosuccinimide in anhydrous CH2Cl2 at room temperature. Further, the resulted compounds undergo… read more here.
Keywords: bromo arylethyl; benzotriazole ring; synthesis bromo; ring cleavage ... See more keywords
CuX Dual Catalysis: Construction of Oxazolo[2,3-b][1,3]oxazines via a Tandem CuAAC/Ring Cleavage/[4+2+3] Annulation Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02705
Abstract: CuX as a simple dual catalyst strategy that promotes the tandem transformations of fused oxazolo[2,3-b][1,3]oxazines has been developed. Copper catalyzed terminal ynones, sulfonyl azides, and nitriles for the CuAAC/ring cleavage/[4+2] annulation reaction, while the halogen… read more here.
Keywords: cuaac ring; cleavage annulation; oxazolo oxazines; ring cleavage ... See more keywords
Cu-Catalyzed Redox-Neutral Ring Cleavage of Cycloketone O-Acyl Oximes: Chemodivergent Access to Distal Oxygenated Nitriles.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03707
Abstract: A chemodivergent copper-catalyzed ring opening of cycloketone oximes via radical-mediated C-C bond cleavage under redox-neutral conditions is described. This method allows the divergent synthesis of γ- and δ-acyloxylated, alkoxylated, and hydroxylated nitriles while avoiding the… read more here.
Keywords: cycloketone; redox neutral; ring cleavage; catalyzed redox ... See more keywords
Emerging Trends of Benzotriazole Ring Cleavage (BtRC) in Organic Synthesis
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DOI: 10.1055/a-2577-1120
Abstract: The distinct structural features of benzotriazole heterocycle facilitates the formation of new bonds and promotes denitrogenation processes for an easy access to physiologically relevant molecules through benzotriazole ring cleavage (BtRC) path. Several important functionalization of… read more here.
Keywords: cleavage btrc; ring cleavage; organic synthesis; benzotriazole ring ... See more keywords
Synthesis of Functionalized 5-Amino-3(2H)-furanones via Base-Catalyzed Ring-Cleavage/Recyclization of 4-Cyano-3(2H)-furanones in the Presence of Water
Sign Up to like & getrecommendations! Published in 2018 at "Synthesis"
DOI: 10.1055/s-0037-1609916
Abstract: 5-Alkyl/aryl/hetaryl-4-cyano-3(2H)-furanones undergo ring-cleavage/recyclization in the presence of water under mild conditions [MOH (M = Na, K), aqueous ethanol, 20–25 °C] to afford 4-acyl/aroyl/hetaroyl-5-amino-3(2Н)-furanones in 75–99% yields. read more here.
Keywords: cyano furanones; amino furanones; cleavage recyclization; ring cleavage ... See more keywords
Electrochemically Catalyzed N–N Coupling and Ring Cleavage Reaction of 1H-Pyrazoles
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DOI: 10.1055/s-0040-1706050
Abstract: The electrocatalyzed N–N coupling and ring cleavage reaction of 3-methyl-, 3,5-dimethyl-, 3-methyl-5-phenyl- and 3,5-diphenyl-1H-pyrazole was investigated and led to the electro-organic synthesis of new heterocyclic compounds. The results revealed that electrochemically produced 1H-pyrazoleox plays the… read more here.
Keywords: reaction pyrazoles; cleavage reaction; coupling ring; reaction ... See more keywords
Four Aromatic Intradiol Ring Cleavage Dioxygenases from Aspergillus niger
Sign Up to like & getrecommendations! Published in 2019 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01786-19
Abstract: Aromatic ring opening using molecular oxygen is one of the critical steps in the degradation of aromatic compounds by microorganisms. While enzymes catalyzing this step have been well-studied in bacteria, their counterparts from fungi are… read more here.
Keywords: aspergillus niger; aromatic compounds; intradiol; ring cleavage ... See more keywords
Separate Upper Pathway Ring Cleavage Dioxygenases Are Required for Growth of Sphingomonas wittichii Strain RW1 on Dibenzofuran and Dibenzo-p-Dioxin
Sign Up to like & getrecommendations! Published in 2021 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02464-20
Abstract: S. wittichii RW1 has been the subject of numerous investigations, because it is one of only a few strains known to grow on DXN as the sole carbon and energy source. However, while the genome… read more here.
Keywords: dxn; dxn degradation; ring cleavage; rw1 ... See more keywords
Solvent-Free Ring Cleavage Hydrazinolysis of Certain Biginelli Pyrimidines
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemistry"
DOI: 10.1155/2018/6354742
Abstract: Certain Biginelli pyrimidines with ester substitution in C5 were subjected to unexpected ring opening upon solvent-free reaction with hydrazine hydrate to give three products: pyrazole, arylidenehydrazines, and urea/thiourea, respectively. The nonisolable carbohydrazide intermediates are formed… read more here.
Keywords: free ring; biginelli pyrimidines; certain biginelli; ring cleavage ... See more keywords