Ring‐Closure on the Rocks in a Prebiotic Environment
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300143
Abstract: Ring‐closure is a key step in current pyrimidine anabolism and one may wonder whether cyclisation reactions could be promoted in the geochemical context at the origins of life, i. e. with the help of minerals. Various… read more here.
Keywords: closure rocks; closure; ring closure; rocks prebiotic ... See more keywords
Adamantyl aziridines via aza-Michael initiated ring closure (aza-MIRC) reaction
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.01.006
Abstract: Abstract An efficient one-pot synthesis of functionalized adamantylaziridines by aza-Michael initiated ring closure (aza-MIRC) reaction of 1-aminoadamantane with α-halogenated Michael acceptors is described. The reaction goes through an aza-Michael intermediate that undergoes an intramolecular nucleophilic… read more here.
Keywords: initiated ring; ring closure; aza; reaction ... See more keywords
Synthesis of Linear to Cyclic Polylactide via a One-Pot Step-Wise Ring-Opening Polymerization and Back-Biting Reaction of Ring Closure Using Magnesium Complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c00935
Abstract: The controllable synthesis of cyclic polylactide remains a challenging topic so far. In this work, a new strategy of one-pot step-wise ring-opening polymerization (ROP) followed by a back-biting reaction of ring closure was reported, in… read more here.
Keywords: reaction; back biting; ring closure; biting reaction ... See more keywords
Ring Closure and Ring Opening as Useful Scaffold Hopping Tools in Agrochemistry.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01416
Abstract: Ring closing acyclic parts of a molecular scaffold or the opposite manipulation, opening rings to produce pseudo-ring structures, is an important scaffold hopping manipulation. Analogues derived from biologically active compounds through the utilization of such… read more here.
Keywords: closure ring; opening useful; ring closure; scaffold hopping ... See more keywords
Two-Step Enzymatic Synthesis of Biocompatible Polymers Made from Cholic Acid
Sign Up to like & getrecommendations! Published in 2017 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.6b02043
Abstract: Polyesters are known biodegradable materials that are frequently used for biomedical applications that require biocompatibility. Their synthesis usually requires transition metal catalysts, which may become a source of contamination. In addition, using such compounds translates… read more here.
Keywords: chemistry; two step; step enzymatic; ring closure ... See more keywords
Direct observation of cyclic poly(N-substituted maleimide)s with broad size distributions synthesized by anionic polymerization using an N-heterocyclic carbene and successive ring closure without high dilutions
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Journal"
DOI: 10.1038/s41428-020-0384-z
Abstract: The N-heterocyclic carbene 1,3-di-tert-butylimidazol-2-ylidene (NHCtBu) and its 1:1 adduct with methyl sorbate (MS) were found to initiate anionic polymerization of N-substituted maleimides (RMIs) in organic solvents at −20 °C to afford linear and cyclic poly(RMI)s, respectively.… read more here.
Keywords: cyclic poly; anionic polymerization; poly; ring closure ... See more keywords
Bis(1-bora-4-phosphorinane) ring closure at Cp*M (M = Fe, Co) complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc07060f
Abstract: Bis(1-bora-4-phosphorinane) metal complexes have been synthesized using a Cp*M-protecting (M = FeIICl, CoI, Cp* = C5Me5-) strategy and structurally authenticated by NMR spectroscopy and single crystal X-ray diffraction. Synthesis of these scaffolds is highly sensitive… read more here.
Keywords: bis bora; bora phosphorinane; spectroscopy; closure complexes ... See more keywords
Iminologous epoxide ring-closure
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04496j
Abstract: The discovery of new reactions enables chemists to attain a better understanding of fundamental chemical reactivity and push the boundaries of organic synthesis. Our understanding and manipulation of high-energy states such as reactive conformations, intermediates,… read more here.
Keywords: 320 320; epoxide ring; ring closure; iminologous epoxide ... See more keywords
Structural Analysis of the Michael-Michael Ring Closure (MIMIRC) Reaction Products
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092810
Abstract: A representative number of decalin and hydrindane derivatives 2a–l were prepared in 11–91% yield by means of a cascade reaction of cyclohexanone/cyclopentanone enolates and methyl acrylate through a Michael–Michael ring closure (MIMIRC) process. The relative… read more here.
Keywords: reaction; michael ring; stereochemistry; ring closure ... See more keywords