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DMSO as a C1 Source for [2 + 2 + 1] Pyrazole Ring Construction via Metal-Free Annulation with Enaminones and Hydrazines.

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Published in 2021 at "Organic letters"

DOI: 10.1021/acs.orglett.1c03879

Abstract: A cascade reaction between enaminones, hydrazines, and dimethyl sulfoxide (DMSO) for the synthesis of 1,4-disubstituted pyrazoles catalyzed by molecular iodine in the presence of Selectfluor has been realized. DMSO plays a dual role as the… read more here.

Keywords: enaminones hydrazines; pyrazole ring; source; source pyrazole ... See more keywords