Mechanistic Insights into Pyridine Ring Degradation Catalyzed by 2,5-Dihydroxypyridine Dioxygenase NicX.
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DOI: 10.1021/acs.inorgchem.1c03370
Abstract: 2,5-Dihydroxypyridine dioxygenase (NicX) from Pseudomonas putida KT2440 is a mononuclear non-heme iron oxygenase that can catalyze the oxidative pyridine ring cleavage. Recently, the reported crystal structure of NicX has lent support to an apical dioxygen… read more here.
Keywords: pyridine ring; ring degradation; dioxygenase nicx; dihydroxypyridine dioxygenase ... See more keywords