Both polarity and aromatic ring in the side chain of tryptophan 246 are involved in binding activity of Vibrio vulnificus hemolysin to target cells.
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DOI: 10.1016/j.micpath.2017.05.029
Abstract: Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis against a variety of mammalian cells by forming pores on the cellular membrane. VVH is known to bind to the cellular membrane as a monomer, and… read more here.
Keywords: vibrio vulnificus; side chain; target; ring side ... See more keywords