Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T) and myelodysplastic syndrome with ring sideroblasts (MDS‐RS)
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DOI: 10.1002/ajh.26182
Abstract: REFERENCES 1. Kumar SK, Callander NS, Hillengass J, et al. NCCN guidelines insights: multiple myeloma, version 1.2020. J Natl Compr Canc Netw. 2019;17 (10):1154-1165. 2. Cheson BD, Leoni L. Bendamustine: mechanism of action and clinical… read more here.
Keywords: genomic transcriptomic; ring sideroblasts; multiple myeloma; myelodysplastic syndrome ... See more keywords
Comparison of therapy-related myelodysplastic syndrome with ring sideroblasts and de novo myelodysplastic syndrome with ring sideroblasts.
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DOI: 10.1016/j.leukres.2019.106227
Abstract: Presence of RS is closely associated with SF3B1 mutation in de novo MDS. RS is also present in a subset of therapy-related MDS (t-MDS), but data is not available in t-MDS with RS (t-MDS-RS). Using… read more here.
Keywords: syndrome ring; ring sideroblasts; mds mds; myelodysplastic syndrome ... See more keywords
Luspatercept for myelodysplastic syndromes/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis
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DOI: 10.1038/s41375-022-01521-4
Abstract: Luspatercept for myelodysplastic syndromes/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis Rami S. Komrokji 1, Uwe Platzbecker , Pierre Fenaux, Amer M. Zeidan, Guillermo Garcia-Manero , Ghulam J. Mufti, Valeria Santini , María Díez-Campelo , Carlo… read more here.
Keywords: myeloproliferative neoplasm; ring sideroblasts; neoplasm ring; myelodysplastic syndromes ... See more keywords
Clinical analysis and literature review of a case with the myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis
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DOI: 10.1080/16078454.2020.1790840
Abstract: ABSTRACT Objective: Myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) is a new disease entity in the 2016 WHO classification, characterized by anemia, thrombocytosis and bone marrow ring sideroblasts. We herein reported a case… read more here.
Keywords: myeloproliferative neoplasm; syndrome myeloproliferative; ring sideroblasts; analysis ... See more keywords
Luspatercept as a therapy for myelodysplastic syndromes with ring sideroblasts
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DOI: 10.1080/17474086.2021.1947791
Abstract: ABSTRACT Introduction Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic stem cell diseases characterized by cell dysplasia, ineffective hematopoiesis and risk of transformation to acute myeloid leukemia (AML). The median age of 75 years… read more here.
Keywords: syndromes ring; myelodysplastic syndromes; ring sideroblasts; therapy myelodysplastic ... See more keywords
Heavy/light chain ratio normalization prior to transplant is of independent prognostic significance in multiple myeloma: a BMT CTN 0102 correlative study
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DOI: 10.1111/bjh.14170
Abstract: Arber, D.A. & Hasserjian, R.P. (2015) Reclassifying myelodysplastic syndromes: what’s where in the new WHO and why. Hematology/the Education Program of the American Society of Hematology, 2015, 294–298. Cui, R., Gale, R.P., Xu, Z., Qin,… read more here.
Keywords: myelodysplastic syndromes; hematology; ring sideroblasts; myelodysplastic syndrome ... See more keywords
Abstract 4344649: Heart Failure in the Hematologic Spectrum: Cardiovascular Toxicity and Targeted Therapy in Myelodysplasia with Ring Sideroblasts
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DOI: 10.1161/circ.152.suppl_3.4344649
Abstract: Background: Myelodysplastic syndrome with ring sideroblasts (MDS-RS) is defined by macrocytic anemia, ineffective erythropoiesis, and ≥15% ring sideroblasts, often linked to SF3B1 mutations. Though lower-risk for leukemia, MDS-RS carries cardiovascular risk due to anemia-induced myocardial… read more here.
Keywords: hematologic cardiac; iron; luspatercept imetelstat; ring sideroblasts ... See more keywords
MDS/MPN with ring sideroblasts and thrombocytosis masquerading as prefibrotic/early primary myelofibrosis.
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DOI: 10.1182/blood-2016-11-749937
Abstract: ![Figure][1] A 75-year-old man was investigated for persistent thrombocytosis/leukocytosis. He had history of night sweats and chronic anemia, but no thrombotic events. He had no splenomegaly and lactate dehydrogenase was persistently elevated (380 U/L). Complete… read more here.
Keywords: mpn ring; ring sideroblasts; thrombocytosis; thrombocytosis masquerading ... See more keywords
Refractory anemia with ring sideroblasts: Epidemiological survival trends and implications in a SEER population-based study
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DOI: 10.1182/blood-2025-7382
Abstract: Introduction: Refractory Anemia with ring sideroblasts (RARS) is a myelodysplastic syndrome (MDS) subtype defined by anemia, dyserythropoiesis, and ≥15% ring sideroblasts in the bone marrow, driven largely by SF3B1 mutations and mitochondrial iron accumulation. It… read more here.
Keywords: population; disease; ring sideroblasts; refractory anemia ... See more keywords
Efficacy of Lenalidomide in Myelodysplastic/Myeloproliferative Neoplasms with Ring Sideroblasts
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DOI: 10.1182/blood.v130.suppl_1.5317.5317
Abstract: Background: Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) with ring sideroblasts and thrombosis (MDS/MPN-RS-T), include the dysplastic features of Refractory Anemia with Ring Sideroblasts (RARS) and the myeloproliferative features of essential thrombocythemia (ET) and are characterized by a high… read more here.
Keywords: platelet count; ring sideroblasts; blood; count ... See more keywords
Myelodysplastic Neoplasms (MDS) with Ring Sideroblasts or SF3B1 Mutations: The Improved Clinical Utility of World Health Organization and International Consensus Classification 2022 Definitions, a Single-Centre Retrospective Chart Review
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DOI: 10.3390/curroncol31040134
Abstract: Myelodysplastic neoplasms (MDS) with ring sideroblasts (RS) are diagnosed via bone marrow aspiration in the presence of either (i) ≥15% RS or (ii) 5–14% RS and an SF3B1 mutation. In the MEDALIST trial and in… read more here.
Keywords: ring sideroblasts; mds ring; 2022 definitions; myelodysplastic neoplasms ... See more keywords