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Cyanomethylation of the Benzene Rings and Pyridine Rings via Direct Oxidative Cross-Dehydrogenative Coupling with Acetonitrile.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c00498

Abstract: A novel and efficient approach for the amine-directed dehydrogenative C(sp2)-C(sp3) coupling of arylamines with acetonitrile was reported by using FeCl2 as the catalyst. Substituted anilines, aminopyridines, naphthylamines, and some nitrogen-containing heterocyclic arylamines react with inactive… read more here.

Keywords: pyridine rings; benzene rings; rings pyridine; cyanomethylation benzene ... See more keywords