Articles with "rip1 perturbation" as a keyword



RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.638382

Abstract: Osteoarthritis (OA) is a highly prevalent and debilitating joint disorder that characterized by progressive destruction of articular cartilage. There is no effective disease-modifying therapy for the condition due to limited understanding of the molecular mechanisms… read more here.

Keywords: chondrocyte necroptosis; necroptosis; pathogenesis; rip1 perturbation ... See more keywords