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   Articles with "rip140" as a keyword



Importance of RIP140 and LCoR Sub-Cellular Localization for Their Association With Breast Cancer Aggressiveness and Patient Survival1

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recommendations! Published in 2018 at "Translational Oncology"

DOI: 10.1016/j.tranon.2018.06.006

Abstract: New markers are needed to improve diagnosis and to personalize treatments for patients with breast cancer (BC). Receptor-interacting protein of 140 kDa (RIP140) and ligand-dependent corepressor (LCoR), two transcriptional co-regulators of estrogen receptors, strongly interact… read more here.

Keywords: rip140 lcor; expression; rip140; cancer ... See more keywords

Knockdown of receptor interacting protein 140 (RIP140) alleviated lipopolysaccharide-induced inflammation, apoptosis and permeability in pulmonary microvascular endothelial cells by regulating C-terminal binding protein 2 (CTBP2)

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2031403

Abstract: ABSTRACT The main pathological feature of acute lung injury (ALI) is pulmonary edema caused by increased permeability of pulmonary microvascular endothelial cells (PMVECs). LPS was has been confirmed to lead to cell damage and barrier… read more here.

Keywords: rip140; lps induced; inflammation apoptosis; permeability ... See more keywords

Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model.

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recommendations! Published in 2021 at "Neuropathology and applied neurobiology"

DOI: 10.1111/nan.12747

Abstract: AIMS Mitochondrial dysfunction and inflammation are at the core of axonal degeneration in several multifactorial neurodegenerative diseases, including multiple sclerosis, Alzheimer's and Parkinson's disease. The transcriptional coregulator RIP140/NRIP1 (receptor-interacting protein 140) modulates these functions in… read more here.

Keywords: modulation mitochondrial; adrenoleukodystrophy; model; rip140 ... See more keywords

RIP140-Mediated NF-κB Inflammatory Pathway Promotes Metabolic Dysregulation in Retinal Pigment Epithelium Cells

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recommendations! Published in 2022 at "Current Issues in Molecular Biology"

DOI: 10.3390/cimb44110393

Abstract: Metabolic dysregulation of the retinal pigment epithelium (RPE) has been implicated in age-related macular degeneration (AMD). However, the molecular regulation of RPE metabolism remains unclear. RIP140 is known to affect oxidative metabolism and mitochondrial biogenesis… read more here.

Keywords: dysregulation retinal; rip140; pigment epithelium; metabolic dysregulation ... See more keywords

Prognostic Relevance of RIP140 and ERβ Expression in Unifocal Versus Multifocal Breast Cancers: A Preliminary Report

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recommendations! Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20020418

Abstract: The aim of this study was to investigate the expression of two nuclear receptor transcriptional coregulators, namely RIP140 (receptor-interacting protein of 140 kDa) and LCoR (ligand-dependent corepressor) in unifocal versus multifocal breast cancers. The expression… read more here.

Keywords: breast; multifocal breast; breast cancers; expression ... See more keywords