One-year efficacy of adjunctive use of Ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy
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DOI: 10.1007/s00417-017-3727-5
Abstract: PurposeThe aim of this study was to evaluate the one-year efficacy, ability to lower intraocular pressure, and tolerability of ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy.MethodsThis prospective, non-comparative,… read more here.
Keywords: intraocular pressure; ripasudil; patients glaucoma; medical therapy ... See more keywords
Descemet stripping only and ripasudil for the treatment of traumatic Descemet's membrane ruptures.
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DOI: 10.1177/11206721221095598
Abstract: PURPOSE Descemet´s membrane ruptures (with a discontinuation of Descemet´s membrane and double detached coiled edges) in the context of complicated anterior segment surgery have rarely been described and its management can be challenging. We report… read more here.
Keywords: descemet stripping; membrane; membrane ruptures; ripasudil ... See more keywords
An update on ripasudil for the treatment of glaucoma and ocular hypertension.
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DOI: 10.1358/dot.2020.56.9.3178110
Abstract: Ripasudil (K-115) is a novel Rho-associated protein kinase (ROCK) inhibitor. The Rho-ROCK pathway regulates key downstream effectors involved in many cellular functions, in particular in the actin cytoskeleton activity. The clinical effects of ripasudil expected… read more here.
Keywords: ripasudil; ocular hypertension; treatment; treatment glaucoma ... See more keywords
Circadian Fluctuation Changes in Intraocular Pressure Measured Using a Contact Lens Sensor in Patients with Glaucoma after the Adjunctive Administration of Ripasudil: A Prospective Study
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DOI: 10.3390/jpm13050800
Abstract: Nocturnal and circadian intraocular pressure (IOP) fluctuations are important issues in glaucoma treatment. Ripasudil 0.4% eye drops, a new glaucoma medication, lowers IOP by increasing aqueous humor outflow through the trabecular meshwork. We aimed to… read more here.
Keywords: fluctuation; iop; intraocular pressure; reduction ... See more keywords