One-year efficacy of adjunctive use of Ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy
Sign Up to like & getrecommendations! Published in 2017 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-017-3727-5
Abstract: PurposeThe aim of this study was to evaluate the one-year efficacy, ability to lower intraocular pressure, and tolerability of ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy.MethodsThis prospective, non-comparative,… read more here.
Keywords: intraocular pressure; ripasudil; patients glaucoma; medical therapy ... See more keywords
Neuroprotective effect of ripasudil on retinal ganglion cells via an antioxidative mechanism
Sign Up to like & getrecommendations! Published in 2025 at "Japanese Journal of Ophthalmology"
DOI: 10.1007/s10384-025-01243-x
Abstract: To evaluate the neuroprotective effect of ripasudil, a rho-kinase inhibitor that is a commercially available glaucoma medication that lowers intraocular pressure. We explored the effects of ripasudil on retinal damage via oxidative stress (OS) in… read more here.
Keywords: via antioxidative; retinal ganglion; ripasudil; ripasudil retinal ... See more keywords
Descemet stripping only and ripasudil for the treatment of traumatic Descemet's membrane ruptures.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of ophthalmology"
DOI: 10.1177/11206721221095598
Abstract: PURPOSE Descemet´s membrane ruptures (with a discontinuation of Descemet´s membrane and double detached coiled edges) in the context of complicated anterior segment surgery have rarely been described and its management can be challenging. We report… read more here.
Keywords: descemet stripping; membrane; membrane ruptures; ripasudil ... See more keywords
An update on ripasudil for the treatment of glaucoma and ocular hypertension.
Sign Up to like & getrecommendations! Published in 2020 at "Drugs of today"
DOI: 10.1358/dot.2020.56.9.3178110
Abstract: Ripasudil (K-115) is a novel Rho-associated protein kinase (ROCK) inhibitor. The Rho-ROCK pathway regulates key downstream effectors involved in many cellular functions, in particular in the actin cytoskeleton activity. The clinical effects of ripasudil expected… read more here.
Keywords: ripasudil; ocular hypertension; treatment; treatment glaucoma ... See more keywords
Circadian Fluctuation Changes in Intraocular Pressure Measured Using a Contact Lens Sensor in Patients with Glaucoma after the Adjunctive Administration of Ripasudil: A Prospective Study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13050800
Abstract: Nocturnal and circadian intraocular pressure (IOP) fluctuations are important issues in glaucoma treatment. Ripasudil 0.4% eye drops, a new glaucoma medication, lowers IOP by increasing aqueous humor outflow through the trabecular meshwork. We aimed to… read more here.
Keywords: fluctuation; iop; intraocular pressure; reduction ... See more keywords