Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation
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DOI: 10.1172/jci.insight.162701
Abstract: As a hallmark of inflammatory bowel disease (IBD), elevated intestinal epithelial cell (IEC) death compromises the gut barrier, activating the inflammatory response and triggering more IEC death. However, the precise intracellular machinery that prevents IEC… read more here.
Keywords: necroptosis; ripk3 dependent; gab1; epithelial gab1 ... See more keywords
Pine Pollen Polysaccharides’ and Sulfated Polysaccharides’ Effects on UC Mice through Modulation of Cell Tight Junctions and RIPK3-Dependent Necroptosis Pathways
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DOI: 10.3390/molecules27227682
Abstract: The purpose of this study is to explore the effects of pine pollen polysaccharides and sulfated polysaccharides on mice with ulcerative colitis and whether they could protect mice from inflammation by regulating the tight junctions… read more here.
Keywords: polysaccharides sulfated; ripk3 dependent; pine pollen; pollen polysaccharides ... See more keywords
Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway
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DOI: 10.7554/elife.52687
Abstract: The squalene-based oil-in-water emulsion (SE) vaccine adjuvant MF59 has been administered to more than 100 million people in more than 30 countries, in both seasonal and pandemic influenza vaccines. Despite its wide use and efficacy,… read more here.
Keywords: cd8 cell; antibody responses; cd8; ripk3 dependent ... See more keywords