RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
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DOI: 10.1172/jci.insight.94979
Abstract: Renal fibrosis is a common pathogenic response to injury in chronic kidney disease (CKD). The receptor-interacting protein kinase-3 (RIPK3), a regulator of necroptosis, has been implicated in disease pathogenesis. In mice subjected to unilateral ureteral… read more here.
Keywords: akt dependent; fibrosis; kidney fibrosis; ripk3 promotes ... See more keywords