RIPK4 regulates cell-cell adhesion in epidermal development and homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac046
Abstract: Epidermal development and maintenance are finely regulated events requiring a strict balance between proliferation and differentiation. Alterations in these processes give rise to human disorders such as cancer or syndromes with skin and annexes defects,… read more here.
Keywords: cell adhesion; ripk4; adhesion; epidermal development ... See more keywords
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/6622439
Abstract: This study was conducted to evaluate the prognostic value of receptor-interacting protein kinase 4 (RIPK4) in ovarian cancer (OC) and its role in tumorigenesis. RNA expression and the corresponding clinical data were obtained from The… read more here.
Keywords: expression; ovarian cancer; overexpression ripk4; ripk4 ... See more keywords
RIPK4 Is an Immune Regulating-Associated Biomarker for Ovarian Cancer and Possesses Generalization Value in Pan-Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/7599098
Abstract: Ovarian cancer (OC) is the most lethal gynecologic cancer. Many studies have reported that RIPK4 (receptor interacting serine/threonine kinase 4) displayed a dysregulated level in many types of tumors. However, its expressions and functions in… read more here.
Keywords: ovarian cancer; pan cancer; ripk4; ripk4 expression ... See more keywords
Rola białka RIPK4 w fizjologii naskórka.
Sign Up to like & getrecommendations! Published in 2021 at "Postepy biochemii"
DOI: 10.18388/pb.2021_370
Abstract: Białka regulujące morfogenezę naskórka zapewniają jego prawidłową budowę oraz funkcję. Mutacje w ich obrębie prowadzą do licznych zaburzeń w pełnionej funkcji. Jednym z takich ostatnio opisanych białek jest kinaza białkowa oddziałująca z receptorem kinaz serynowo-treoninowych… read more here.
Keywords: bia ripk4; ripk4; bia; nask rka ... See more keywords
The NOTCH-RIPK4-IRF6-ELOVL4 Axis Suppresses Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030737
Abstract: Simple Summary The aim of our study is to understand the signaling mechanisms behind the tumor suppressive function of RIPK4 (receptor-interacting serine/threonine protein kinase 4) in squamous cell carcinomas (SCCs) of skin, head, and neck… read more here.
Keywords: ripk4 irf6; squamous cell; ripk4; irf6 ... See more keywords
Vemurafenib and Dabrafenib Downregulates RIPK4 Level
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DOI: 10.3390/cancers15030918
Abstract: Simple Summary RIPK4 kinase has oncogenic functions in melanoma and shows high similarity to BRAF protein, making this kinase sensitive to the BRAF inhibitors vemurafenib and dabrafenib. BRAFi downregulates RIPK4 in both BRAF-mutated and wild-type… read more here.
Keywords: braf; kinase; ripk4; downregulates ripk4 ... See more keywords
Depletion of RIPK4 parallels higher malignancy potential in cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.12932
Abstract: Background The RIPK4 (receptor-interacting protein kinase 4), a member of the RIPK family, acts as an important regulator of epidermal differentiation, cutaneous inflammation, and cutaneous wound repair. However, Until now, the role of RIPK4 in… read more here.
Keywords: cell; malignancy; expression; ripk4 ... See more keywords