Steric stabilization of RIPL peptide-conjugated liposomes and in vitro assessment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Investigation"
DOI: 10.1007/s40005-018-0392-6
Abstract: RIPL peptide-conjugated liposomes (PEG-RIPL-Ls) were sterically stabilized with polyethylene glycol (PEG) to prevent recognition by the mononuclear phagocytic system (MPS) and prolong their systemic circulation in vivo. PEG-modified maleimide-derivatized liposomes were prepared by a thin-film… read more here.
Keywords: peptide conjugated; ripl peptide; steric stabilization; peg3k ripl ... See more keywords
RIPL peptide-conjugated nanostructured lipid carriers for enhanced intracellular drug delivery to hepsin-expressing cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s166021
Abstract: Background To facilitate selective and enhanced drug delivery to hepsin (Hpn)-expressing cancer cells, RIPL peptide (IPLVVPLRRRRRRRRC, 16-mer)-conjugated nanostructured lipid carriers (RIPL-NLCs) were developed. Methods NLCs were prepared using a solvent emulsification-evaporation method and the RIPL… read more here.
Keywords: ripl peptide; drug delivery; drug; dtx ... See more keywords