Identification of Caveolae-Associated Protein 4 Autoantibodies as a Biomarker of Immune-Mediated Rippling Muscle Disease in Adults
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.1357
Abstract: Key Points Question Is there an autoantibody biomarker of immune-mediated rippling muscle disease (iRMD)? Findings In this cohort study, autoantibodies to caveolae-associated protein 4 (cavin-4) were identified and orthogonally validated in 8 of 10 patients… read more here.
Keywords: biomarker immune; disease; immune mediated; muscle ... See more keywords
Teaching Video NeuroImages: Rippling muscle disease with caveolin myopathy
Sign Up to like & getrecommendations! Published in 2018 at "Neurology"
DOI: 10.1212/wnl.0000000000006427
Abstract: A 43-year-old man described adolescence-onset abnormal muscle contractions. On examination, there was hypertrophy (figure) with normal power of thigh muscles but mild weakness of distal leg muscles (Medical Research Council grade 4+/5). Muscle percussion and… read more here.
Keywords: muscle; muscle disease; rippling muscle; video neuroimages ... See more keywords
Rippling Muscle Disease with Irregular Toe Jerks and Anti-acetylcholine Receptor Antibodies: Remission after Extended Thymectomy.
Sign Up to like & getrecommendations! Published in 2021 at "Internal medicine"
DOI: 10.2169/internalmedicine.8146-21
Abstract: We herein report a 63-year-old rippling muscle disease (RMD) patient who presented with painless stiffness, muscle hypertrophy and muscle contractions elicited by mechanical stimulation. He also showed irregular toe jerks and a slightly elevated level… read more here.
Keywords: muscle; toe jerks; rippling muscle; irregular toe ... See more keywords