Combined transcriptomic and ChIPseq analyses of the Bordetella pertussis RisA regulon
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DOI: 10.1128/msystems.00951-23
Abstract: ABSTRACT The regulation of Bordetella pertussis virulence is mediated by the two-component system BvgA/S, which activates the transcription of virulence-activated genes (vags). In the avirulent phase, the vags are not expressed, but instead, virulence-repressed genes… read more here.
Keywords: pertussis; risa binding; virulence; risa ... See more keywords
The contribution of BvgR, RisA, and RisS to global gene regulation, intracellular cyclic-di-GMP levels, motility, and biofilm formation in Bordetella bronchiseptica
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2024.1305097
Abstract: Bordetella bronchiseptica is a highly contagious respiratory bacterial veterinary pathogen. In this study the contribution of the transcriptional regulators BvgR, RisA, RisS, and the phosphorylation of RisA to global gene regulation, intracellular cyclic-di-GMP levels, motility,… read more here.
Keywords: risa; risa riss; bvgr risa; gene regulation ... See more keywords