The rise and rise of protein degradation: opportunities and challenges ahead.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.08.006
Abstract: The transformational mechanism of action underpinning targeted protein degradation strategies, including proteolysis-targeting chimeras (PROTACs), gives potential for potent in vivo pharmacology and has allowed projects to move rapidly to the clinic. Despite this remarkable progress,… read more here.
Keywords: degradation; rise; rise protein; degradation opportunities ... See more keywords
Rise and rise of the abc transporter families.
Sign Up to like & getrecommendations! Published in 2019 at "Research in microbiology"
DOI: 10.1016/j.resmic.2019.08.004
Abstract: This review will inevitably be influenced by my personal experience and personal view of the progression of this amazing family of proteins. This has generated a huge literature in over nearly five decades, some ideas… read more here.
Keywords: abc transporter; rise; rise abc; rise rise ... See more keywords
Profile: Yoshinori Ohsumi: The rise and rise of a biology superstar
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/543s19a
Abstract: Nobel laureate Yoshinori Ohsumi's persistent study of baker's yeast spawned an exciting new field, and proves the value of supporting scientists in pursuit of their passion read more here.
Keywords: ohsumi rise; rise; profile yoshinori; yoshinori ohsumi ... See more keywords
The rise and rise of lithium
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemistry"
DOI: 10.1038/s41557-021-00638-w
Abstract: We’re in the middle of an energy revolution, argues Bruce C. Gibb, and chemistry is an integral part of it. read more here.
Keywords: rise; chemistry; rise lithium; rise rise ... See more keywords
The Rise and Rise of Medicinal Cannabis, What Now? Medicinal Cannabis Prescribing in Australia 2017–2022
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19169853
Abstract: Medicinal cannabis was legalised in Australia in November 2016. By August 2022, there were 5284 specialist physician and general practitioner (GP) prescribers who submitted Special Access Scheme (SAS) applications to the Therapeutic Goods Administration (TGA)… read more here.
Keywords: rise medicinal; medicinal cannabis; cannabis; rise rise ... See more keywords