Associations of PARP-1 variant rs1136410 with PARP activities, oxidative DNA damage, and the risk of age-related cataract in a Chinese Han population: A two-stage case-control analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2016.11.019
Abstract: OBJECTIVE To investigate whether a single nucleotide polymorphism (SNP) rs1136410 in the poly (ADP-ribose) polymerase-1 (PARP-1) gene was associated with PARP activities, 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels, and the risk of age-related cataract (ARC) in a Chinese… read more here.
Keywords: rs1136410; arc; parp activities; risk age ... See more keywords
Evaluation of disparities in multiple sclerosis risk by age, sex, and nativity in Kuwait:1980-2019.
Sign Up to like & getrecommendations! Published in 2020 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2020.102676
Abstract: OBJECTIVE This cross-sectional cohort study quantified the disparities in MS risk by age, sex, nativity from 1980 to 2019 in Kuwait. METHODS Age-standardized MS incidence rate (ASIR) (per 100,000 person-years) overall and by subcohorts defined… read more here.
Keywords: nativity; age; risk age; 1980 2019 ... See more keywords
Associations of TLR4 gene polymorphisms with the risk of age-related macular degeneration in a Chinese Han population
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000015583
Abstract: Abstract The study was designed to reveal the relationship of toll-like receptor 4 (TLR4, rs1927914 and rs1927907) polymorphisms with risk of age-related macular degeneration (AMD), as well as the adjustment of this association by some… read more here.
Keywords: risk age; age related; amd; age ... See more keywords
Osteoarthritis Is Associated With an Increased Risk of Age-Related Macular Degeneration: A Population-Based Longitudinal Follow-Up Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.854629
Abstract: Aims To investigate the long-term risk of age-related macular degeneration (AMD) in persons with osteoarthritis (OA). Methods This retrospective cohort study first enrolled 71,609 subjects diagnosed with OA, and 236,169 without such a diagnosis between… read more here.
Keywords: related macular; age related; age; risk ... See more keywords
The Risk of Age-Related Macular Degeneration Is Reduced in Type 2 Diabetes Patients Who Use Metformin
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020224
Abstract: Background: Whether metformin may reduce the risk of age-related macular degeneration (AMD) requires confirmation. This study compared the risk of AMD between ever users and never users of metformin matched on propensity score (PS) in… read more here.
Keywords: ever users; risk; never users; risk age ... See more keywords