A novel lipidomics-based approach to evaluating the risk of clinical hepatotoxicity potential of drugs in 3D human microtissues.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.9b00364
Abstract: The importance of adsorption, distribution, metabolism excretion and toxicity (ADMET) analysis is expected to grow substantially due to recent failures in detecting severe toxicity issues of new chemical entities during preclinical/clinical development. Traditionally, safety risk… read more here.
Keywords: hepatotoxicity potential; risk; drug; clinical hepatotoxicity ... See more keywords
Recommendations for high-risk clinical target volume definition with computed tomography for three-dimensional image-guided brachytherapy in cervical cancer patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrw109
Abstract: Abstract Our purpose was to develop recommendations for contouring the computed tomography (CT)-based high-risk clinical target volume (CTVHR) for 3D image-guided brachytherapy (3D-IGBT) for cervical cancer. A 15-member Japanese Radiation Oncology Study Group (JROSG) committee… read more here.
Keywords: computed tomography; high risk; target volume; oncology ... See more keywords
Prediction for High Risk Clinical Symptoms of Epilepsy Based on Deep Learning Algorithm
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Access"
DOI: 10.1109/access.2018.2883562
Abstract: Accurate forecasting of high-risk clinical symptoms, like epileptic seizures, has the potential to transform clinical epilepsy care and to create new therapeutic strategies for individuals in clinical decision support systems. With the development of pervasive… read more here.
Keywords: high risk; deep learning; clinical symptoms; prediction ... See more keywords
The syndemic effects of adverse mental health conditions and polysubstance use on being at risk of clinical depression among marginally housed and homeless transitional age youth living in San Francisco, California
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265397
Abstract: The objective of this study was to identify the correlates of being at risk of clinical depression and examine the role of syndemic factors among marginally housed and homeless transitional age youth (TAY). From 2017–2018,… read more here.
Keywords: risk; clinical depression; risk clinical; use ... See more keywords