First-Trimester Antibiotic Use for Urinary Tract Infection and Risk of Congenital Malformations
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.19544
Abstract: Key Points Question Are nitrofurantoin, trimethoprim-sulfamethoxazole (TMP-SMX), or fluoroquinolones associated with a higher risk of congenital malformations than β-lactams when used to treat urinary tract infection (UTI) during pregnancy? Findings In this cohort study of… read more here.
Keywords: tract infection; risk; risk congenital; congenital malformations ... See more keywords
Prenatal Opioid Use Disorder and the Risk of Congenital Anomalies in Offspring: A Population‐Based Study
Sign Up to like & getrecommendations! Published in 2025 at "Birth Defects Research"
DOI: 10.1002/bdr2.2456
Abstract: To examine whether prenatal opioid use disorder (OUD) diagnosis is associated with the risk of congenital anomalies (CAs) in offspring. read more here.
Keywords: use disorder; prenatal opioid; opioid use; risk congenital ... See more keywords
Antiretroviral drug exposure in pregnancy and risk of congenital anomalies: a European case/non-case malformed study
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-025-03814-w
Abstract: Antiretroviral drugs are recommended during pregnancy to achieve HIV viral suppression and reduce mother-to-child transmission. Congenital anomaly signals were reported after fetal exposure to antiretroviral drugs in several studies warranting further investigation. We aimed to… read more here.
Keywords: case non; antiretroviral drugs; risk congenital; congenital anomalies ... See more keywords
Does the ex utero intrapartum treatment to extracorporeal membrane oxygenation procedure change morbidity outcomes for high-risk congenital diaphragmatic hernia survivors?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2016.10.010
Abstract: PURPOSE In high-risk congenital diaphragmatic hernia (CDH), significant barotrauma or death can occur before extracorporeal membrane oxygenation (ECMO) can be initiated. We previously examined ex utero intrapartum treatment (EXIT)-to-ECMO in our most severe CDH patients,… read more here.
Keywords: congenital diaphragmatic; risk; risk congenital; high risk ... See more keywords
A TBX5 3′UTR variant increases the risk of congenital heart disease in the Han Chinese population
Sign Up to like & getrecommendations! Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2017.26
Abstract: TBX5 is a vital transcription factor involved in cardiac development in a dosage-dependent manner. But little is known about the potential association of TBX5 3′ untranslated region (UTR) variations with congenital cardiac malformations. This study… read more here.
Keywords: tbx5; risk congenital; han chinese; tbx5 utr ... See more keywords
Blastocyst quality and congenital malformation risk in singleton births after frozen embryo transfer
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DOI: 10.1038/s41598-025-20150-2
Abstract: The relationship between blastocyst morphological quality and the risk of congenital malformations in assisted reproductive technology (ART) remains poorly understood, limiting clinical decision-making for embryo selection. We conducted a retrospective cohort study of 3986 frozen… read more here.
Keywords: quality; blastocyst; risk congenital; congenital malformations ... See more keywords
Early Left Ventricular Dysfunction and Severe Pulmonary Hypertension Predict Adverse Outcomes in “Low-Risk” Congenital Diaphragmatic Hernia
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Critical Care Medicine"
DOI: 10.1097/pcc.0000000000002318
Abstract: Objectives: Given significant focus on improving survival for “high-risk” congenital diaphragmatic hernia, there is the potential to overlook the need to identify risk factors for suboptimal outcomes in “low-risk” congenital diaphragmatic hernia cases. We hypothesized… read more here.
Keywords: diaphragmatic hernia; risk congenital; dysfunction; congenital diaphragmatic ... See more keywords
Risk of Congenital Toxoplasmosis in Newborns from Mothers with Documented Infection: Experience from Two Referral Centres
Sign Up to like & getrecommendations! Published in 2025 at "Pathogens"
DOI: 10.3390/pathogens14020157
Abstract: During pregnancy, primary Toxoplasma gondii infection can cause congenital toxoplasmosis (CT). We described the newborns’ outcomes from a multicentre cohort of mothers with seroconversion (SC) at different gestational ages. This retrospective observational study (from 2007… read more here.
Keywords: gondii infection; risk congenital; infection; pregnancy ... See more keywords