The Changing Landscape of Management of Metastatic Renal Cell Carcinoma: Current Treatment Options and Future Directions
Sign Up to like & getrecommendations! Published in 2019 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-019-0638-1
Abstract: Opinion statementFor the practicing clinician, the dilemma becomes how most appropriate to sequence the aforementioned regimens. It is challenging to be dogmatic, as there are no comparative studies juxtaposing novel front-line options directly—all of the… read more here.
Keywords: treatment; disease; risk disease; good risk ... See more keywords
Habitat loss and the risk of disease outbreak
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Environmental Economics and Management"
DOI: 10.1016/j.jeem.2021.102451
Abstract: Evidence suggests that emerging infectious diseases, such as COVID-19, originate from wildlife species, and that land-use change is an important pathway for pathogen transmission to humans. We first focus on zoonotic disease spillover and the… read more here.
Keywords: disease outbreak; risk; disease; risk disease ... See more keywords
Wearing-off at the end of natalizumab dosing interval and risk of MS disease activity: A prospective 1-year follow-up study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2020.116880
Abstract: Natalizumab effectively prevents disease activity in relapsing-remitting multiple sclerosis by binding α4 integrin and inhibiting leukocyte migration to the central nervous system. We recently reported an association between low natalizumab receptor occupancy and subjective wearing-off… read more here.
Keywords: risk disease; disease activity; year; disease ... See more keywords
Using machine learning to estimate survival curves for patients receiving an increased risk for disease transmission heart, liver, or lung versus waiting for a standard organ
Sign Up to like & getrecommendations! Published in 2019 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13181
Abstract: Over 19% of deceased organ donors are labeled increased risk for disease transmission (IRD) for viral blood‐borne disease transmission. Many potential organ recipients need to decide between accepting an IRD organ offer and waiting for… read more here.
Keywords: risk disease; disease transmission; increased risk; disease ... See more keywords
Disease Characteristics of Minority Patient Populations with Polycythemia Vera: An Analysis from the Reveal Study
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-112530
Abstract: Introduction: Polycythemia vera (PV) is associated with increased blood cell counts, risk of thrombosis, and symptoms including fatigue and pruritus. Few studies have examined the presence or absence of racial/ethnic disparities among patients with PV.… read more here.
Keywords: caucasian patients; caucasian non; risk disease; non caucasian ... See more keywords
Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007569
Abstract: Key Points • Patients who underwent core needle biopsy are more likely to have poor-risk disease features and inadequate tissue for molecular analyses.• Increasing tissue requirements of biomarker-driven trials may exclude patients with high-risk DLBCL… read more here.
Keywords: increasing tissue; trials may; risk; risk disease ... See more keywords
A randomized phase II trial of pazopanib (PAZ) vs. temsirolimus (TEM) in patients (pts) with advanced clear-cell renal cell carcinoma (accRCC) with intermediate or poor-risk disease (the TemPa trial).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.4563
Abstract: 4563Background: TEM has level 1 evidence in aRCC with poor-risk disease. No previous trial compared a VEGFR-TKI with TEM as first-line (1L) therapy. Methods: We randomly assigned (1:1) treatment-na... read more here.
Keywords: poor risk; trial; risk disease; cell ... See more keywords
Shifting patterns of care in localized prostate cancer: Impact on patient reported outcome measures (PROMs).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e16603
Abstract: e16603 Background: In localized prostate cancer (LPC), evolving therapeutic techniques and patterns of care including the use of active surveillance (AS) are expected to have had a positive effect on quality of life. A longitudinal… read more here.
Keywords: risk disease; patterns care; risk; prostate cancer ... See more keywords
Association between diabetes mellitus, prediabetes and risk, disease progression of Parkinson's disease: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1109914
Abstract: Background Previous studies reported inconsistent results regarding association between diabetes mellitus (DM), prediabetes and risk, disease progression of Parkinson's disease (PD). The meta-analysis was made to investigate association between DM, prediabetes and risk, disease progression… read more here.
Keywords: disease; progression; disease progression; association ... See more keywords
Sphingolipid Levels and Signaling via Resveratrol and Antioxidant Actions in Cardiometabolic Risk and Disease
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12051102
Abstract: Resveratrol (RSV) is a phenolic compound with strong antioxidant activity, which is generally associated with the beneficial effects of wine on human health. All resveratrol-mediated benefits exerted on different systems and pathophysiological conditions are possible… read more here.
Keywords: risk disease; sphingolipid levels; oxidative stress; resveratrol ... See more keywords
Stereotactic radiotherapy of the prostate: fractionation and utilization in the United States
Sign Up to like & getrecommendations! Published in 2017 at "Radiation Oncology Journal"
DOI: 10.3857/roj.2017.02026
Abstract: Purpose To analyze the utilization and fractionation of extreme hypofractionation via stereotactic body radiotherapy (SBRT) in the treatment of prostate cancer. Materials and Methods Data was analyzed on men diagnosed with localized prostate cancer between… read more here.
Keywords: prostate; utilization; fractionation; risk disease ... See more keywords