PNPLA3 rs738409 and risk of fibrosis in NAFLD: Exploring mediation pathways through intermediate histological features
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DOI: 10.1002/hep.32491
Abstract: It is unclear whether rs738409 (p.I148M) missense variant in patatin‐like phospholipase domain‐containing 3 rs738409 promotes fibrosis development by triggering specific fibrogenic pathways or by creating an unfavorable microenvironment by promoting steatosis, inflammation, and ultimately fibrosis.… read more here.
Keywords: pnpla3 rs738409; fibrosis nafld; rs738409 risk; risk fibrosis ... See more keywords
Nomogram for Quantitatively Estimating the Risk of Fibrosis Progression in Type 2 Diabetic Patients With Nonalcoholic Fatty Liver Disease: A Pilot Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.917304
Abstract: Background Correct identification of the fibrosis progression risk is a critical step in the management of patients with type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD), because liver fibrosis, especially advanced liver… read more here.
Keywords: progression; risk fibrosis; fibrosis progression; fibrosis ... See more keywords