Phase 1 trial of adavosertib (AZD1775) in combination with concurrent radiation and cisplatin for intermediate-risk and high-risk head and neck squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer"
DOI: 10.1002/cncr.33789
Abstract: BACKGROUND Adavosertib (AZD1775) is an inhibitor of the Wee1 kinase. The authors conducted a phase 1b trial to evaluate the safety of adavosertib in combination with definitive chemoradiotherapy for patients with newly diagnosed, intermediate-risk/high-risk, locally… read more here.
Keywords: combination; phase; risk; high risk ... See more keywords
The impact of body mass index on the risk of high spinal block in parturients undergoing cesarean delivery: a retrospective cohort study
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DOI: 10.1007/s00540-017-2352-0
Abstract: PurposeTo investigate the hypothesis that the risk of high spinal block is not increased in obese parturients undergoing cesarean delivery compared to non-obese parturients.MethodsThis is a retrospective study at an academic center. We searched the… read more here.
Keywords: block; bmi; delivery; cesarean delivery ... See more keywords
Predicting High-risk and High-cost Patients for Proactive Intervention
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DOI: 10.1097/mlr.0000000000001737
Abstract: Background: It is well known that 20% of the patients incur 80% of health care costs and many diseases and complications can be prevented or ameliorated with prompt intervention. One of the well-recognized strategies for… read more here.
Keywords: proactive intervention; patients proactive; cost; high risk ... See more keywords
Association of lifestyle factors with blood lipids and inflammation in adults aged 40 years and above: a population-based cross-sectional study in Taiwan
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DOI: 10.1186/s12889-019-7686-0
Abstract: Lifestyle factors were associated with an increased risk of cardiovascular disease (CVD) occurrence. We explored the associations between lifestyle factors and CVD risk factors, and assessed the interactive effects of lifestyle factors on CVD risk… read more here.
Keywords: risk; risk factors; cvd risk; factors cvd ... See more keywords
Oncological and functional outcomes of high-risk and very high-risk prostate cancer patients after robot-assisted radical prostatectomy
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DOI: 10.1371/journal.pone.0282494
Abstract: Purpose This study investigated the oncological and functional outcomes of robot-assisted radical prostatectomy (RaRP) in high-risk and very high-risk prostate cancer patients. Materials and methods One hundred localized prostate cancer patients receiving RaRP from August… read more here.
Keywords: prostate cancer; high risk; cancer patients; risk group ... See more keywords