Constitutional BRCA1 Methylation and Risk of Incident Triple-Negative Breast Cancer and High-grade Serous Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2022.3846
Abstract: Key Points Question Is mosaic BRCA1 promoter methylation in normal tissue associated with the risk of incident high-grade serous ovarian cancer (HGSOC) and triple-negative breast cancer (TNBC)? Findings In this nested case-control study including 637… read more here.
Keywords: brca1; methylation; high grade; risk incident ... See more keywords
Risk of incident autoimmune diseases in patients with thymectomy
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51055
Abstract: The data concerning the association between Tx and ADs remain unclear and are scarce. This study was undertaken to investigate whether people with Tx are more likely to develop ADs, compared to those without Tx. read more here.
Keywords: diseases patients; neurology; risk incident; autoimmune diseases ... See more keywords
BP and Risk of Incident AD Dementia by Antihypertensive and APOE ε4 allele
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25228
Abstract: Objective To examine the association of blood pressure (BP) with incident Alzheimer’s disease (AD) dementia. read more here.
Keywords: risk incident; antihypertensive apoe; incident dementia; dementia ... See more keywords
Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4664
Abstract: We investigated independent associations between telomere length and risk of fracture and arthroplasty in UK Biobank participants. Leukocyte telomere length (LTL) was measured in baseline samples using a validated polymerase chain reaction (PCR) method. We… read more here.
Keywords: fracture; telomere length; incident fracture; risk incident ... See more keywords
Serum copper-to-zinc-ratio and risk of incident infection in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Epidemiology"
DOI: 10.1007/s10654-020-00644-1
Abstract: Infections are one of the main causes of mortality in elderly due to the decrease of immune response, for which copper (Cu) and zinc (Zn) are claimed to be crucial. High serum copper-to-zinc-ratio ( Cu/Zn-ratio)… read more here.
Keywords: risk; copper zinc; risk incident; incident infection ... See more keywords
Does heart failure increase the risk of incident cancer? A meta-analysis and systematic review
Sign Up to like & getrecommendations! Published in 2019 at "Heart Failure Reviews"
DOI: 10.1007/s10741-019-09876-0
Abstract: Recently, several studies have demonstrated that heart failure (HF) may increase the risk of incident cancer. However, this association has not been statistically and systematically verified by any comprehensive pooled analyses. We performed a meta-analysis… read more here.
Keywords: risk incident; risk; heart failure; incident cancer ... See more keywords
Gout and the risk of incident depression in older adults
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2018.10.067
Abstract: We used the 5% random Medicare claims from Americans 65 years or older from 2006-2012 to examine the association of gout with the risk of developing incident (new) depression using multivariable-adjusted Cox proportional hazards model,… read more here.
Keywords: depression; risk incident; depression older; gout risk ... See more keywords
Dietary fibre intake in relation to the risk of incident chronic kidney disease
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Nutrition"
DOI: 10.1017/s0007114517003671
Abstract: Abstract The purpose of this study was primarily to evaluate the association of total fibre intake with the risk of incident chronic kidney disease (CKD). We also evaluated the association of dietary fibre from fruits,… read more here.
Keywords: risk incident; dietary fibre; incident; ckd ... See more keywords
Fish consumption and risk of incident dementia in elderly Japanese: the Ohsaki cohort 2006 study
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Nutrition"
DOI: 10.1017/s0007114519002265
Abstract: Abstract Fish harbour many types of nutrients that are beneficial for preventing cognitive decline. Therefore, habitual fish intake might contribute to a lower risk of incident dementia. However, few prospective cohort studies have investigated fish… read more here.
Keywords: incident dementia; risk incident; fish consumption; consumption ... See more keywords
Potential for repurposing oral hypertension/diabetes drugs to decrease asthma risk in obesity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asthma"
DOI: 10.1080/02770903.2022.2097919
Abstract: Abstract Objective Risk for asthma in the overweight/obese may be mediated by adiponectin and peroxisome proliferator activated receptor pathways and may be reduced by the use of oral drugs impacting these pathways, such as angiotensin… read more here.
Keywords: incident asthma; hypertension; asthma; ace ... See more keywords
Risk of Rheumatoid Arthritis in Patients with Endometriosis: A Nationwide Population-Based Cohort Study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of women's health"
DOI: 10.1089/jwh.2020.8431
Abstract: Background: Abnormalities in the immune system of endometriosis has been demonstrated and may reflect the chronic inflammatory response or the autoimmune reaction to the presence of ectopic endometrial tissue. Rheumatoid arthritis (RA) is a chronic… read more here.
Keywords: risk incident; risk; patients endometriosis; study ... See more keywords