A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2023 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-223570
Abstract: Objectives To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular model of transmitochondrial cybrids. Methods Three prospective… read more here.
Keywords: risk rapid; mtdna variant; mtdna; knee ... See more keywords
Validation of a scoring system to evaluate the risk of rapid growth of intracranial meningiomas in neurofibromatosis type 2 patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurosurgery"
DOI: 10.3171/2020.3.jns192382
Abstract: OBJECTIVE Intracranial meningiomas occur in about half of neurofibromatosis type 2 (NF2) patients and are very frequently multiple. Thus, estimating individual meningiomas' growth rates is of great interest to tailor therapeutic interventions. The Asan Intracranial… read more here.
Keywords: growth; risk rapid; meningiomas; intracranial meningiomas ... See more keywords