Association between polymorphisms of Xeroderma pigmentosum complementation group C gene (XPC) and susceptibility to schizophrenia.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.02.018
Abstract: Previous studies revealed that polymorphisms in several DNA repair genes are associated with the risk of schizophrenia. The relationship between three polymorphisms (Ala499Val, PAT, and Lys939Gln) of the XPC (MIM: 613208) and the risk of… read more here.
Keywords: schizophrenia; association; risk schizophrenia; xpc ... See more keywords
Emotional word usage in groups at risk for schizophrenia-spectrum disorders: An objective investigation of attention to emotion
Sign Up to like & getrecommendations! Published in 2017 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2017.01.098
Abstract: Both extreme levels of social anhedonia (SocAnh) and extreme levels of perceptual aberration/magical ideation (PerMag) indicate increased risk for schizophrenia-spectrum disorders and are associated with emotional deficits. For SocAnh, there is evidence of self-reported decreased… read more here.
Keywords: schizophrenia spectrum; spectrum disorders; group; attention ... See more keywords
Association between obsessive-compulsive disorder and the risk of schizophrenia using the Korean National Health Insurance Service-National Sample Cohort: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2023 at "Epidemiology and Psychiatric Sciences"
DOI: 10.1017/s2045796023000021
Abstract: Abstract Aims Obsessive-compulsive disorder (OCD) and schizophrenia are often reported as co-morbid conditions. However, the evidence of an association between OCD and the risk of schizophrenia is limited. This study investigated the risk of schizophrenia… read more here.
Keywords: sample cohort; korean national; schizophrenia; risk schizophrenia ... See more keywords
Grey and white matter microstructure is associated with polygenic risk for schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Psychiatry"
DOI: 10.1038/s41380-021-01260-5
Abstract: Recent discovery of approximately 270 common genetic variants associated with schizophrenia has enabled polygenic risk scores (PRS) to be measured in the population. We hypothesized that normal variation in PRS would be associated with magnetic… read more here.
Keywords: polygenic risk; risk; risk schizophrenia; white matter ... See more keywords
Age at first birth in women is genetically associated with increased risk of schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28160-z
Abstract: Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a… read more here.
Keywords: age first; risk; schizophrenia; first birth ... See more keywords
Perinatal iron deficiency as an early risk factor for schizophrenia.
Sign Up to like & getrecommendations! Published in 2021 at "Nutritional neuroscience"
DOI: 10.1080/1028415x.2021.1943996
Abstract: Growing evidence indicates that a suboptimal intrauterine environment confers risk for schizophrenia. The developmental model of schizophrenia posits that aberrant brain growth during early brain development and adolescence may interact to contribute to this psychiatric… read more here.
Keywords: risk; iron deficiency; early risk; risk schizophrenia ... See more keywords
A comparative study of theory of mind in taxon-like clusters of psychometric schizotypes and individuals at genetic risk for schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Cognitive Neuropsychiatry"
DOI: 10.1080/13546805.2022.2147814
Abstract: ABSTRACT Introduction: Clinical and family studies suggest that alterations of theory of mind (ToM) represent a marker of genetic liability to schizophrenia. Findings regarding ToM in schizotypy are less consistent. The study aimed to explore… read more here.
Keywords: risk schizophrenia; individuals genetic; theory mind; psychometric schizotypes ... See more keywords
O8.1. ASSOCIATION BETWEEN GENETIC AND ENVIRONMENTAL RISK FOR SCHIZOPHRENIA DURING UPBRINGING: FINDINGS FROM A LONGITUDINAL COHORT STUDY
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa028.042
Abstract: Abstract Background Associations of environmental exposures such as urban upbringing, deprivation and crime victimization with psychosis are well-established. An enduring question, however, is whether associations reflect a causal process. Emerging evidence using polygenic risk scores… read more here.
Keywords: schizophrenia; risk; family; risk schizophrenia ... See more keywords
Rare FBXO18 variations and risk of schizophrenia: Whole‐exome sequencing in two parent‐affected offspring trios followed by resequencing and case–control studies
Sign Up to like & getrecommendations! Published in 2017 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.12526
Abstract: Rare variations are suggested to play a role in the genetic etiology of schizophrenia; to further investigate their role, we performed a three‐stage study in a Japanese population. read more here.
Keywords: variations risk; fbxo18 variations; schizophrenia whole; rare fbxo18 ... See more keywords
No association between dopamine D3 receptor gene Ser9Gly polymorphism (rs6280) and risk of schizophrenia: an updated meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s152784
Abstract: Objective Ser9Gly (rs6280) is a functional single-nucleotide polymorphism (SNP) in the dopamine receptor D3 (DRD3) gene that may be associated with schizophrenia. We performed a meta-analysis to determine whether Ser9Gly influences the risk of schizophrenia… read more here.
Keywords: schizophrenia; analysis; association; risk schizophrenia ... See more keywords
Irreversible Primary Visual Cortex Impairment in a Mouse Model of High-Risk Schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s246163
Abstract: Purpose Although visual deficits can be observed at any stage of schizophrenia, few studies have focused on visual cortex alterations in individuals at high risk of schizophrenia. This study aimed to investigate the pathological changes… read more here.
Keywords: visual cortex; high risk; risk schizophrenia; schizophrenia ... See more keywords