Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.12259
Abstract: This case-control study assesses the association of a genetic risk score based on variants in a DNA repair pathway with risk of a second primary contralateral breast cancer after radiation therapy for a first breast… read more here.
Keywords: risk; contralateral breast; risk score; breast cancer ... See more keywords
Exploration of Overdose Risk Score and Postoperative Complications and Health Care Use After Total Knee Arthroplasty
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.13977
Abstract: This cohort study investigates the association of an overdose risk score with postoperative complications and health care use after total knee arthroplasty. read more here.
Keywords: health care; complications health; risk score; postoperative complications ... See more keywords
Transferability of Alzheimer Disease Polygenic Risk Score Across Populations and Its Association With Alzheimer Disease-Related Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.47162
Abstract: Key Points Question Is a polygenic risk score (PRS) derived from European ancestry data associated with Alzheimer disease (AD) dementia risk in non-European populations? Findings In this cohort study of genome data from European and… read more here.
Keywords: disease; alzheimer disease; risk score; polygenic risk ... See more keywords
Systematic evaluation of cancer‐specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2143
Abstract: Genetic risk score (GRS) is an odds ratio (OR)‐weighted and population‐standardized method for measuring cumulative effect of multiple risk‐associated single nucleotide polymorphisms (SNPs). We hypothesize that GRS is a valid tool for risk assessment of… read more here.
Keywords: risk; risk score; systematic evaluation; cancer ... See more keywords
Bioinformatic profiling identifies a platinum‐resistant–related risk signature for ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2692
Abstract: Most high‐grade serous ovarian cancer (HGSOC) patients develop resistance to platinum‐based chemotherapy and recur. Many biomarkers related to the survival and prognosis of drug‐resistant patients have been delved by mining databases; however, the prediction effect… read more here.
Keywords: risk; risk score; resistance; signature ... See more keywords
Admission high‐sensitivity C‐reactive protein levels improve the Grace risk score prediction on in‐hospital outcomes in acute myocardial infarction patients
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23749
Abstract: Acute myocardial infarction (AMI) is the main cause of death and disability in cardiovascular and cerebrovascular diseases. Both the Global Registry of Acute Coronary Events (Grace) score and high‐sensitivity C‐reactive protein (hs‐CRP) were associated with… read more here.
Keywords: risk score; grace; myocardial infarction; acute myocardial ... See more keywords
The effect of weight on labor market outcomes: An application of genetic instrumental variables
Sign Up to like & getrecommendations! Published in 2019 at "Health Economics"
DOI: 10.1002/hec.3828
Abstract: Abstract This paper contributes to the literature on the labor market consequences of obesity by using a novel instrument: genetic risk score, which reflects the predisposition to higher body mass index (BMI) across many genetic… read more here.
Keywords: risk score; risk; genetic risk; labor market ... See more keywords
Prospective assessment of a nasopharyngeal carcinoma risk score in a population undergoing screening
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33424
Abstract: Despite evidence suggesting the utility of Epstein‐Barr virus (EBV) markers to stratify individuals with respect to nasopharyngeal carcinoma (NPC) risk in NPC high‐risk regions, no validated NPC risk prediction model exists. We aimed to validate… read more here.
Keywords: risk; risk score; npc risk; score ... See more keywords
Integrated analysis of a competing endogenous RNA network reveals key long noncoding RNAs as potential prognostic biomarkers for hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28655
Abstract: Growing evidence has revealed that long noncoding RNAs (lncRNAs) have an important impact on tumorigenesis and tumor progression via a mechanism involving competing endogenous RNAs (ceRNAs). However, their use in predicting the survival of a… read more here.
Keywords: risk score; score system; risk; network ... See more keywords
A risk score for predicting death in COVID‐19 in‐hospital infection: A Brazilian single‐center study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23195
Abstract: There is a paucity of information about Brazilian COVID‐19 in‐hospital mortality probability of death combining risk factors. read more here.
Keywords: death; covid; risk score; covid hospital ... See more keywords
A Claims‐Based Frailty Risk Score Is Associated With Hospitalization for Acute‐on‐Chronic Liver Failure: But Is It Frailty?
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DOI: 10.1002/lt.25921
Abstract: Frailty is a multidimensional construct that broadly refers to a health-state of diminished physiologic reserve resulting in a reduced tolerance to health stressors.(1) Although the concept of frailty has its roots in geriatrics, it has… read more here.
Keywords: claims based; risk; frailty risk; risk score ... See more keywords