A risk signature of three autophagy-related genes for predicting lower grade glioma survival is associated with tumor immune microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.10.008
Abstract: Treatment for lower-grade gliomas (LGG) has been challenging. Though emerging approaches such as immunotherapy is promising, it is still faced with immune tolerance, an obstacle that may be overcome by targeting autophagy-related (ATG) genes. After… read more here.
Keywords: immune; risk; lower grade; autophagy related ... See more keywords
Identification of 5 microRNA biomarkers associated with the prognosis of uveal melanoma
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DOI: 10.1097/md.0000000000030366
Abstract: To uncover the role of microRNAs in the occurrence and development of uveal melanoma (UM), we used R language packages in this study to analyze the correlations between the expression of microRNA isoforms, their target… read more here.
Keywords: identification microrna; melanoma; uveal melanoma; microrna biomarkers ... See more keywords
A lipid metabolism-related risk signature for patients with gliomas constructed with TCGA and CGGA data
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030501
Abstract: Lipid metabolism affects cell proliferation, differentiation, membrane homeostasis and drug resistance. An in-depth exploration of lipid metabolism in gliomas might provide a novel direction for gliomas treatment. A lipid metabolism-related risk signature was constructed in… read more here.
Keywords: metabolism related; risk; lipid metabolism; risk signature ... See more keywords
Cuproptosis-associated genes and immune microenvironment characterization in breast cancer
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DOI: 10.1097/md.0000000000032301
Abstract: Excess Cu can cause cell death as a cofactor for essential enzymes. The relationship between cuproptosis-associated genes (CAGs) and breast cancer (BR) is not completely investigated. Here, the transcriptome expression and mutation profile data of… read more here.
Keywords: cuproptosis associated; cuproptosis; risk; cancer ... See more keywords
A risk signature of necroptosis-related lncRNA to predict prognosis and probe molecular characteristics for male with bladder cancer
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033664
Abstract: Bladder cancer (BC) is a frequently diagnosed cancer with high mortality. Male patients have a higher risk of developing BC than female patients. As a type of caspase-independent cell death, necroptosis plays a significant role… read more here.
Keywords: necroptosis; signature; risk; analysis ... See more keywords
Bioinformatics Analysis Reveals an Association between Autophagy, Prognosis, Tumor Microenvironment, and Immunotherapy in Osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4220331
Abstract: Autophagy is a catabolic pathway involved in the regulation of bone homeostasis. We explore clinical correlation of autophagy-related key molecules to establish risk signature for predicting the prognosis, tumor microenvironment (TME), and immunotherapy response of… read more here.
Keywords: tumor microenvironment; risk; risk signature;
Construction and Validation of a Novel Cuproptosis-Related Seven-lncRNA Signature to Predict the Outcomes, Immunotherapeutic Responses, and Targeted Therapy in Patients with Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Disease Markers"
DOI: 10.1155/2023/7219794
Abstract: Background Cuproptosis was recently recognized as a novel form of cell death, linked closely to the occurrence and progression of cancer. We aimed to identify prognostic cuproptosis-related long noncoding RNAs (lncRNAs) and build a risk… read more here.
Keywords: cell; signature; risk; cuproptosis related ... See more keywords
Development and validation of a prognostic risk signature for lung adenocarcinoma constructed by six ferroptosis, necroptosis, and pyroptosis-related lncRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thoracic Disease"
DOI: 10.21037/jtd-22-1151
Abstract: Background Identifying populations that benefit from immune checkpoint blockade (ICB) therapy remains a major challenge in the treatment of lung adenocarcinoma (LUAD). Existing programmed cell death (PCD) related prognostic models only consider a single mechanism,… read more here.
Keywords: pyroptosis; related lncrnas; risk; ferroptosis ... See more keywords
Identification of a Nomogram with an Autophagy-Related Risk Signature for Survival Prediction in Patients with Glioma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s335571
Abstract: Background Glioma is a common type of tumor in the central nervous system characterized by high morbidity and mortality. Autophagy plays vital roles in the development and progression of glioma, and is involved in both… read more here.
Keywords: related risk; signature; risk; analysis ... See more keywords
A Novel Inflammatory-Related Gene Signature Based Model for Risk Stratification and Prognosis Prediction in Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.798131
Abstract: Inflammation is an important hallmark of cancer and plays a role in both neogenesis and tumor development. Despite this, inflammatory-related genes (IRGs) remain to be poorly studied in lung adenocarcinoma (LUAD). We aim to explore… read more here.
Keywords: risk; risk signature; prognosis; signature ... See more keywords
Prognostic value and immunological characteristics of a novel cuproptosis-related long noncoding RNAs risk signature in kidney renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1009555
Abstract: Background: Cuproptosis has been found as a novel cell death mode significantly associated with mitochondrial metabolism, which may be significantly associated with the occurrence and growth of tumors. LncRNAs take on critical significance in regulating… read more here.
Keywords: cuproptosis; kirc patients; signature; risk ... See more keywords