A risk signature of three autophagy-related genes for predicting lower grade glioma survival is associated with tumor immune microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.10.008
Abstract: Treatment for lower-grade gliomas (LGG) has been challenging. Though emerging approaches such as immunotherapy is promising, it is still faced with immune tolerance, an obstacle that may be overcome by targeting autophagy-related (ATG) genes. After… read more here.
Keywords: immune; risk; lower grade; autophagy related ... See more keywords
RNA-seq and bulk RNA-seq data analysis of cancer-related fibroblasts (CAF) in LUAD to construct a CAF-based risk signature
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-74336-1
Abstract: Angiogenesis, metastasis, and resistance to therapy are all facilitated by cancer-associated fibroblasts (CAFs). A CAF-based risk signature can be used to predict patients’ prognoses for Lung adenocarcinoma (LUAD) based on CAF characteristics. The Gene Expression… read more here.
Keywords: rna seq; analysis; risk; risk signature ... See more keywords
Identification of 5 microRNA biomarkers associated with the prognosis of uveal melanoma
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DOI: 10.1097/md.0000000000030366
Abstract: To uncover the role of microRNAs in the occurrence and development of uveal melanoma (UM), we used R language packages in this study to analyze the correlations between the expression of microRNA isoforms, their target… read more here.
Keywords: identification microrna; melanoma; uveal melanoma; microrna biomarkers ... See more keywords
A lipid metabolism-related risk signature for patients with gliomas constructed with TCGA and CGGA data
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DOI: 10.1097/md.0000000000030501
Abstract: Lipid metabolism affects cell proliferation, differentiation, membrane homeostasis and drug resistance. An in-depth exploration of lipid metabolism in gliomas might provide a novel direction for gliomas treatment. A lipid metabolism-related risk signature was constructed in… read more here.
Keywords: metabolism related; risk; lipid metabolism; risk signature ... See more keywords
Cuproptosis-associated genes and immune microenvironment characterization in breast cancer
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DOI: 10.1097/md.0000000000032301
Abstract: Excess Cu can cause cell death as a cofactor for essential enzymes. The relationship between cuproptosis-associated genes (CAGs) and breast cancer (BR) is not completely investigated. Here, the transcriptome expression and mutation profile data of… read more here.
Keywords: cuproptosis associated; cuproptosis; risk; cancer ... See more keywords
A risk signature of necroptosis-related lncRNA to predict prognosis and probe molecular characteristics for male with bladder cancer
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033664
Abstract: Bladder cancer (BC) is a frequently diagnosed cancer with high mortality. Male patients have a higher risk of developing BC than female patients. As a type of caspase-independent cell death, necroptosis plays a significant role… read more here.
Keywords: necroptosis; signature; risk; analysis ... See more keywords
A disulfidptosis-related classification and risk signature identifies immunotherapy biomarkers and predicts prognosis in gastric cancer: An observational study
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DOI: 10.1097/md.0000000000038398
Abstract: Gastric cancer (GC) is one of the most prevalent types of cancer globally, often detected at advanced stages. However, its prognosis remains poor, necessitating the exploration of new biomarkers. Disulfidptosis, a recently identified form of… read more here.
Keywords: cancer; disulfidptosis; risk signature; gastric cancer ... See more keywords
Development of a novel risk signature revealing prognostic and tumor microenvironmental features in breast cancer
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DOI: 10.1097/md.0000000000041369
Abstract: This study aimed to devise a breast cancer (BC) risk signature for based on pyrimidine metabolism-related genes (PMRGs) to evaluate its prognostic value and association with drug sensitivity. Transcriptomic and clinical data were retrieved from… read more here.
Keywords: cancer; risk; prognosis; risk signature ... See more keywords
Bioinformatics Analysis Reveals an Association between Autophagy, Prognosis, Tumor Microenvironment, and Immunotherapy in Osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/4220331
Abstract: Autophagy is a catabolic pathway involved in the regulation of bone homeostasis. We explore clinical correlation of autophagy-related key molecules to establish risk signature for predicting the prognosis, tumor microenvironment (TME), and immunotherapy response of… read more here.
Keywords: tumor microenvironment; risk; risk signature;
Construction and Validation of a Novel Cuproptosis-Related Seven-lncRNA Signature to Predict the Outcomes, Immunotherapeutic Responses, and Targeted Therapy in Patients with Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Disease Markers"
DOI: 10.1155/2023/7219794
Abstract: Background Cuproptosis was recently recognized as a novel form of cell death, linked closely to the occurrence and progression of cancer. We aimed to identify prognostic cuproptosis-related long noncoding RNAs (lncRNAs) and build a risk… read more here.
Keywords: cell; signature; risk; cuproptosis related ... See more keywords
Identification of a PANoptosis-related long noncoding rna risk signature for prognosis and immunology in colon adenocarcinoma
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DOI: 10.1186/s12885-025-14021-2
Abstract: PANoptosis, a complex programmed cell death (PCD) pathway that includes apoptosis, pyroptosis and necroptosis, is significantly involved in the progression of cancers. Long noncoding RNAs (lncRNAs) play crucial roles in PCD. However, the predictive value… read more here.
Keywords: immunology; analysis; risk; risk signature ... See more keywords