Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes.
Sign Up to like & getrecommendations! Published in 2018 at "Epigenomics"
DOI: 10.2217/epi-2018-0003
Abstract: AIM To identify functional lung adenocarcinoma (LUAD) risk SNPs. MATERIALS & METHODS Eighteen validated LUAD risk SNPs (p ≤ 5 × 10-8) and 930 SNPs in high linkage disequilibrium (r2 > 0.5) were integrated with epigenomic information from primary human alveolar… read more here.
Keywords: lung adenocarcinoma; luad risk; human alveolar; risk snps ... See more keywords
Identification of a Risk Locus at 7p22.3 for Schizophrenia and Bipolar Disorder in East Asian Populations
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.789512
Abstract: Background: Shared psychopathological features and mechanisms have been observed between schizophrenia (SZ) and bipolar disorder (BD), but their common risk genes and full genetic architectures remain to be fully characterized. The genome-wide association study (GWAS)… read more here.
Keywords: risk; east asian; risk snps; genome wide ... See more keywords