Neurobehavioral Differences of Valproate and Risperidone on MK-801 Inducing Acute Hyperlocomotion in Mice
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DOI: 10.1155/2022/1048463
Abstract: Objective The glutamate system plays a major role in the development of neuropsychiatric disorders such as addiction, epilepsy, dementia, and psychosis. MK-801 (dizocilpine), an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, could increase locomotor activity and stereotyped… read more here.
Keywords: hyperlocomotion; risperidone valproic; risperidone; valproic acid ... See more keywords