RKI-1447, a Rho kinase inhibitor, causes ocular hypotension, actin stress fiber disruption, and increased phagocytosis
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DOI: 10.1007/s00417-018-4175-6
Abstract: PurposeThis study investigated the hypotensive effect of RKI-1447, a Rho kinase inhibitor, in a porcine ex vivo pigmentary glaucoma model.MethodsTwenty-eight porcine anterior chambers were perfused with medium supplemented with 1.67 × 107 pigment particles/ml for 48 h before… read more here.
Keywords: phagocytosis; rki 1447; pigment; rho kinase ... See more keywords