Successful spinal cord stimulation for severe medication‐refractory restless legs syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27644
Abstract: Restless legs syndrome (RLS) is characterized by an urge to move the legs, classically accompanied by uncomfortable sensations. Symptoms typically worsen during rest and at night. Pharmacotherapy includes levodopa/dopamine agonists, anticonvulsants (alpha-2-delta ligands), opioids, and… read more here.
Keywords: improvement; stimulation; scs; medication ... See more keywords
Structural neuroimaging findings in migraine patients with restless legs syndrome
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DOI: 10.1007/s00234-020-02451-7
Abstract: Purpose One out of three migraine patients might have accompanying restless legs syndrome (RLS). In our study, we aimed to compare the volumes of the brain structures of migraineurs with and without RLS. Methods We… read more here.
Keywords: rls patients; legs syndrome; migraine patients; rls ... See more keywords
Restless legs syndrome in people with multiple sclerosis: An updated systematic review and meta-analyses.
Sign Up to like & getrecommendations! Published in 2021 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2021.103275
Abstract: BACKGROUND Restless legs syndrome (RLS) is a sensory-motor disorder characterized by an uncomfortable sensation felt in the lower extremity. The aim of this systematic review and meta-analyses was (i) to provide updated information on the… read more here.
Keywords: multiple sclerosis; review; legs syndrome; rls ... See more keywords
Hyperdopaminergism in lenticulostriate stroke-related restless legs syndrome: an imaging study.
Sign Up to like & getrecommendations! Published in 2017 at "Sleep medicine"
DOI: 10.1016/j.sleep.2016.02.011
Abstract: OBJECTIVE The pathophysiology of restless legs syndrome (RLS) involves a dopaminergic dysregulation that remains poorly understood, with controversial data from the literature. Stroke-related RLS is a rare condition that involves primarily the basal ganglia, the… read more here.
Keywords: stroke related; legs syndrome; rls; stroke ... See more keywords
Diurnal variation of default mode network in patients with restless legs syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "Sleep medicine"
DOI: 10.1016/j.sleep.2017.09.031
Abstract: OBJECTIVE Restless legs syndrome (RLS) patients compared to controls have been found to have abnormal patterns in the default mode network (DMN) in the morning when symptom threshold is the highest and symptoms are least… read more here.
Keywords: default mode; morning; mode network; legs syndrome ... See more keywords
Polysomnographic findings in restless legs syndrome (RLS) patients with severe augmentation.
Sign Up to like & getrecommendations! Published in 2018 at "Sleep medicine"
DOI: 10.1016/j.sleep.2018.04.010
Abstract: BACKGROUND AND OBJECTIVES Augmentation can occur frequently in restless legs syndrome (RLS) patients treated with dopaminergic agents. Video-polysomnographic (PSG) data from augmented RLS patients are scant. The aim of this study was to evaluate PSG findings… read more here.
Keywords: rls patients; augmentation; legs syndrome; augmented rls ... See more keywords
Restless legs syndrome severity in the National RLS Opioid Registry during the COVID-19 pandemic
Sign Up to like & getrecommendations! Published in 2022 at "Sleep Medicine"
DOI: 10.1016/j.sleep.2022.01.011
Abstract: Objective/Background No research has yet assessed the impact of the coronavirus disease 2019 (COVID-19) pandemic on restless legs syndrome (RLS). We hypothesized that RLS symptom severity would be increased during the COVID-19 pandemic in a… read more here.
Keywords: restless legs; legs syndrome; symptom severity; rls ... See more keywords
0796 Dipyridamole for the Treatment of RLS: Preliminary Results of a Cross-Over, Placebo-Controlled, Double-Blind Trial
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DOI: 10.1093/sleep/zsaa056.792
Abstract: Recent animal models of restless legs syndrome (RLS) suggest that brain iron deficiency is associated with a hypoadenosinergic state, with downregulation of adenosine A1 receptors (A1R) in the striatum. Dipyridamole is a non-selective inhibitor of… read more here.
Keywords: treatment; dipyridamole; placebo; day ... See more keywords
Baseline and One-Year Longitudinal Data from the National Restless Legs Syndrome Opioid Registry.
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DOI: 10.1093/sleep/zsaa183
Abstract: STUDY OBJECTIVES Restless Legs Syndrome (RLS) is a sensory-motor neurological disorder. Low dose opioid medications are prescribed for treatment-refractory RLS. We describe baseline and 1-year longitudinal dosing and symptom outcomes for the National RLS Opioid… read more here.
Keywords: one year; year; baseline; opioid ... See more keywords
0698 Contrasting Painful and Painless Restless Legs Phenotypes: An Adult Twin Family Study
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DOI: 10.1093/sleep/zsad077.0698
Abstract: Several studies characterized painful and painless restless legs syndrome (RLS) phenotypes based on clinical, topographical, polysomnographic, and genetic background. One pediatric twin family study demonstrated a clear contrast between these two forms of RLS. The… read more here.
Keywords: iron deficiency; adult; pain; rls ... See more keywords
0709 Chronotype characteristics in restless legs syndrome
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DOI: 10.1093/sleep/zsad077.0709
Abstract: There are many people with a late chronotype in restless legs syndrome(RLS) patients. This phenomenon may be caused by sleep disturbance due to lower extremity symptoms of RLS, or it may be caused by some… read more here.
Keywords: late chronotype; chronotype; group; restless legs ... See more keywords