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   Articles with "rna" as a keyword



Escherichia coli tRNA 2‐selenouridine synthase (SelU) converts S2U‐RNA to Se2U‐RNA via S‐geranylated‐intermediate

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recommendations! Published in 2018 at "FEBS Letters"

DOI: 10.1002/1873-3468.13124

Abstract: To date the only tRNAs containing nucleosides modified with a selenium (5‐carboxymethylaminomethyl‐2‐selenouridine and 5‐methylaminomethyl‐2‐selenouridine) have been found in bacteria. By using tRNA anticodon‐stem‐loop fragments containing S2U, Se2U, or geS2U, we found that in vitro tRNA… read more here.

Keywords: s2u rna; rna; rna se2u; se2u ... See more keywords

Abiogenesis through gradual evolution of autocatalysis into template‐based replication

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14507

Abstract: How life emerged from inanimate matter is one of the most intriguing questions posed to modern science. Central to this research are experimental attempts to build systems capable of Darwinian evolution. RNA catalysts (ribozymes) are… read more here.

Keywords: template based; rna; autocatalytic systems; based replication ... See more keywords

An update on post‐transcriptional regulation of retrotransposons

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14551

Abstract: Retrotransposons, including LINE‐1, Alu, SVA, and endogenous retroviruses, are one of the major constituents of human genomic repetitive sequences. Through the process of retrotransposition, some of them occasionally insert into new genomic locations by a… read more here.

Keywords: update post; rna; regulation; post transcriptional ... See more keywords

Probing the legitimate initiation of RNA synthesis by Qβ replicase with oligonucleotide primers

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recommendations! Published in 2024 at "FEBS Letters"

DOI: 10.1002/1873-3468.14833

Abstract: Oligoribonucleotides complementary to the template 3′ terminus were tested for their ability to initiate RNA synthesis on legitimate templates capable of exponential amplification by Qβ replicase. Oligonucleotides shorter than the distance to the nearest predicted… read more here.

Keywords: initiation; probing legitimate; rna synthesis; rna ... See more keywords

Selection of bifunctional RNAs with specificity for arginine and lipid membranes

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recommendations! Published in 2024 at "FEBS Letters"

DOI: 10.1002/1873-3468.14880

Abstract: The molecular mechanisms of selective RNA loading into exosomes and other extracellular vesicles are not yet completely understood. In order to show that a pool of RNA sequences binds both the amino acid arginine and… read more here.

Keywords: rna 10arg; arginine lipid; bifunctional rnas; rna ... See more keywords

High‐throughput detection of RNA modifications at single base resolution

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recommendations! Published in 2024 at "Febs Letters"

DOI: 10.1002/1873-3468.15052

Abstract: RNA is modified by > 170 chemical modifications that affect its structure and function. Accordingly, RNA modifications have been implicated in regulation of gene expression and cellular outcomes in a variety of species spanning the phylogenetic… read more here.

Keywords: high throughput; base resolution; single base; rna ... See more keywords

Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases

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recommendations! Published in 2025 at "FEBS Letters"

DOI: 10.1002/1873-3468.70038

Abstract: Fanzor proteins represent the first confirmed family of RNA‐guided DNA endonucleases in eukaryotes. Originally identified in 2013 as TnpB homologs, Fanzors remained functionally uncharacterized until 2023, when three independent research groups demonstrated their activity as… read more here.

Keywords: dna endonucleases; family; rna guided; rna ... See more keywords

Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment

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recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13322

Abstract: We previously observed increased levels of adenosine‐deaminase‐acting‐on‐dsRNA (Adar)‐dependent RNA editing during mesothelioma development in mice exposed to asbestos. The aim of this study was to characterize and assess the role of ADAR‐dependent RNA editing in… read more here.

Keywords: rna editing; adar2; rna; mesothelioma ... See more keywords

Methylation of N6 adenosine‐related long noncoding RNA: effects on prognosis and treatment in ‘driver‐gene‐negative’ lung adenocarcinoma

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recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13323

Abstract: The improvement of treatment for patients with ‘driver‐gene‐negative’ lung adenocarcinoma (LUAD) remains a critical problem to be solved. We aimed to explore the role of methylation of N6 adenosine (m6A)‐related long noncoding RNA (lncRNA) in… read more here.

Keywords: negative lung; gene negative; driver gene; rna ... See more keywords

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow-up biomarkers for breast cancer.

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recommendations! Published in 2025 at "Molecular oncology"

DOI: 10.1002/1878-0261.70101

Abstract: Breast cancer (BC) diagnostics and prognostics traditionally rely on invasive tissue biopsies, presenting limitations for large-scale screening and continuous patient monitoring. Salivary biomarkers have recently emerged as a compelling noninvasive and accessible alternative, offering significant… read more here.

Keywords: oncology; breast cancer; rna; salivary rna ... See more keywords
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Regulation of Neisseria meningitidis cytochrome bc 1 components by NrrF, a Fur‐controlled small noncoding RNA

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recommendations! Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12266

Abstract: NrrF is a small regulatory RNA of the human pathogen Neisseria meningitidis. NrrF was previously shown to repress succinate dehydrogenase (sdhCDAB) under control of the ferric uptake regulator (Fur). Here, we provide evidence that cytochrome… read more here.

Keywords: cytochrome components; rna; cytochrome bc1; meningitidis cytochrome ... See more keywords