An endogenous bornavirus‐like nucleoprotein in miniopterid bats retains the RNA‐binding properties of the original viral protein
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14290
Abstract: Endogenous bornavirus‐like nucleoprotein elements (EBLNs) are sequences derived from bornaviral N genes in vertebrate genomes. Some EBLNs have been suggested to encode functional proteins in host cells; however, little is known about their evolution and… read more here.
Keywords: rna binding; like nucleoprotein; endogenous bornavirus; protein ... See more keywords
Genomic Accumulation of Retrotransposons Was Facilitated by Repressive RNA‐Binding Proteins: A Hypothesis
Sign Up to like & getrecommendations! Published in 2019 at "BioEssays"
DOI: 10.1002/bies.201800132
Abstract: Retrotransposon-derived elements (RDEs) can disrupt gene expression, but are nevertheless widespread in metazoan genomes. This review presents a hypothesis that repressive RNA-binding proteins (RBPs) facilitate the large-scale accumulation of RDEs. Many RBPs bind RDEs in… read more here.
Keywords: accumulation; binding proteins; rna; rna binding ... See more keywords
New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer
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DOI: 10.1002/cac2.12254
Abstract: With the development of proteomics and epigenetics, a large number of RNA‐binding proteins (RBPs) have been discovered in recent years, and the interaction between long non‐coding RNAs (lncRNAs) and RBPs has also received increasing attention.… read more here.
Keywords: rna binding; long non; coding rnas; binding proteins ... See more keywords
Novel roles for RNA binding proteins squid, hephaesteus, and Hrb27C in Drosophila oogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.550
Abstract: Reproductive capacity in many organisms is maintained by germline stem cells (GSCs). A complex regulatory network influences stem cell fate, including intrinsic factors, local signals, and hormonal and nutritional cues. Posttranscriptional regulatory mechanisms ensure proper… read more here.
Keywords: rna binding; novel roles; squid hephaesteus; proteins squid ... See more keywords
The role of cold‐inducible RNA binding protein in cell stress response
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DOI: 10.1002/ijc.30833
Abstract: Cold‐inducible RNA binding protein (CIRP) was discovered after the cells were exposed to a moderate cold shock because its production was induced. Other cellular stresses such as ultraviolet light radiation and hypoxia also could increase… read more here.
Keywords: inducible rna; rna binding; binding protein; cold inducible ... See more keywords
RNA‐binding proteins in diabetic microangiopathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24407
Abstract: As the most common complication of diabetes, the diabetic microangiopathy characterizes diabetic retinopathy (DR) and nephropathy (DN). Diabetic microangiopathy has always been a serious clinical problem. A wide variety of nucleic acid interacting factors called… read more here.
Keywords: proteins diabetic; rna binding; binding proteins; diabetic microangiopathy ... See more keywords
TRIM25 and its emerging RNA‐binding roles in antiviral defense
Sign Up to like & getrecommendations! Published in 2020 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1588
Abstract: The innate immune system is the body's first line of defense against viruses, with pattern recognition receptors (PRRs) recognizing molecules unique to viruses and triggering the expression of interferons and other anti‐viral cytokines, leading to… read more here.
Keywords: emerging rna; defense; rna binding; trim25 ... See more keywords
Molecular and biological functions of TRIM‐NHL RNA‐binding proteins
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DOI: 10.1002/wrna.1620
Abstract: The TRIM‐NHL family of proteins shares a conserved domain architecture and play crucial roles in stem cell biology, fertility, and development. This review synthesizes new insights that have revolutionized our understanding of the molecular and… read more here.
Keywords: biological functions; rna; rna binding; trim nhl ... See more keywords
RBPmap: A Tool for Mapping and Predicting the Binding Sites of RNA-Binding Proteins Considering the Motif Environment.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1851-6_3
Abstract: RNA-binding proteins (RBPs) play a key role in post-transcriptional regulation via binding to coding and non-coding RNAs. Recent development in experimental technologies, aimed to identify the targets of RBPs, has significantly broadened our knowledge on… read more here.
Keywords: rbpmap; binding proteins; mapping predicting; rna binding ... See more keywords
PAR-CLIP: A Method for Transcriptome-Wide Identification of RNA Binding Protein Interaction Sites.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1851-6_9
Abstract: During post-transcriptional gene regulation (PTGR), RNA binding proteins (RBPs) interact with all classes of RNA to control RNA maturation, stability, transport, and translation. Here, we describe Photoactivatable-Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation (PAR-CLIP), a transcriptome-scale method for… read more here.
Keywords: clip method; par clip; rna; rna binding ... See more keywords
In Vitro Assays for RNA Binding and Protein Priming of Hepatitis B Virus Polymerase.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6700-1_13
Abstract: The hepatitis B virus (HBV) polymerase synthesizes the viral DNA genome from the pre-genomic RNA (pgRNA) template through reverse transcription. Initiation of viral DNA synthesis is accomplished via a novel protein priming mechanism, so named… read more here.
Keywords: protein; dna; rna binding; protein priming ... See more keywords