The landscape of RNA-chromatin interaction reveals small non-coding RNAs as essential mediators of leukemia maintenance
Sign Up to like & getrecommendations! Published in 2024 at "Leukemia"
DOI: 10.1038/s41375-024-02322-7
Abstract: RNA constitutes a large fraction of chromatin. Spatial distribution and functional relevance of most of RNA-chromatin interactions remain unknown. We established a landscape analysis of RNA-chromatin interactions in human acute myeloid leukemia (AML). In total… read more here.
Keywords: non coding; rna chromatin; coding rnas; chromatin ... See more keywords
Stress-induced RNA–chromatin interactions promote endothelial dysfunction
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DOI: 10.1038/s41467-020-18957-w
Abstract: Chromatin-associated RNA (caRNA) has been proposed as a type of epigenomic modifier. Here, we test whether environmental stress can induce cellular dysfunction through modulating RNA-chromatin interactions. We induce endothelial cell (EC) dysfunction with high glucose… read more here.
Keywords: chromatin interactions; induced rna; dysfunction; stress ... See more keywords