Rixosomal RNA degradation contributes to silencing of Polycomb target genes.
Sign Up to like & getrecommendations! Published in 2022 at "Nature"
DOI: 10.1038/s41586-022-04598-0
Abstract: Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate1-3. Multiple… read more here.
Keywords: target genes; rna degradation; polycomb target; degradation ... See more keywords
Loss of Polycomb proteins CLF and LHP1 leads to excessive RNA degradation in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac216
Abstract: Polycomb-group (PcG) proteins are major chromatin complexes that regulate gene expression, mainly described as repressors keeping genes in a transcriptional silent state during development. Recent studies have nonetheless suggested that PcG proteins might have additional… read more here.
Keywords: polycomb; active genes; rna degradation; pcg proteins ... See more keywords
Control of RNA degradation in cell fate decision
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1164546
Abstract: Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.… read more here.
Keywords: cell fate; cell; rna degradation; control rna ... See more keywords