A new type of circular RNA derived from nonconventional introns in nuclear genes of euglenids.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.166758
Abstract: Nuclear protein-coding genes of euglenids (Discoba, Euglenozoa, Euglenida) contain conventional (spliceosomal) and nonconventional introns. The latter have been found only in euglenozoans. A unique feature of nonconventional introns is the ability to form a stable… read more here.
Keywords: nonconventional introns; new type; rna derived; circular rna ... See more keywords
Transfer RNA-derived small RNA: a Rising Star in Oncology.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2021.05.024
Abstract: Transfer RNAs (tRNAs) participate in protein synthesis through delivering amino acids to the ribosome. Nevertheless, recent studies revealed that tRNAs can undergo cleavage by endoribonucleases to generate a heterogeneous class of small RNAs, designated as… read more here.
Keywords: rna derived; derived small; rna; transfer rna ... See more keywords
Export of RNA-derived modified nucleosides by equilibrative nucleoside transporters defines the magnitude of autophagy response and Zika virus replication.
Sign Up to like & getrecommendations! Published in 2021 at "RNA biology"
DOI: 10.1080/15476286.2021.1960689
Abstract: RNA contains a wide variety of posttranscriptional modifications covalently attached to its base or sugar group. These modified nucleosides are liberated from RNA molecules as the consequence of RNA catabolism and released into extracellular space,… read more here.
Keywords: export; rna derived; modified nucleosides; autophagy response ... See more keywords
Y RNA derived small RNAs in Sjögren's syndrome: Candidate biomarkers?
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13229
Abstract: Anti‐Ro and anti‐La antibodies are important in pathogenesis and diagnosis of Sjögren's syndrome (SS). Ro60, Ro52 and La are RNA binding proteins of Y RNA, which were discovered more than three decades ago. Significance of… read more here.
Keywords: gren syndrome; rna derived; rnas gren; derived small ... See more keywords
Altered Expressions of Transfer RNA-Derived Small RNAs and microRNAs in the Vitreous Humor of Proliferative Diabetic Retinopathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.913370
Abstract: Purpose We sought to reveal the expression profiles of transfer RNA-derived small RNAs (tsRNAs) and microRNAs (miRNAs) in the vitreous humor of patients with proliferative diabetic retinopathy (PDR). Methods Vitreous humor samples were obtained from… read more here.
Keywords: transfer rna; rna derived; vitreous humor; small rnas ... See more keywords
Transfer RNA-Derived Small RNAs: Novel Regulators and Biomarkers of Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.843598
Abstract: Transfer RNA-derived small RNAs (tsRNAs) are conventional non-coding RNAs (ncRNAs) with a length between18 and 40 nucleotides (nt) playing a crucial role in treating various human diseases including tumours. Nowadays, with the use of high-throughput… read more here.
Keywords: transfer rna; rna derived; rnas novel; derived small ... See more keywords
Transfer RNA-Derived Fragments and isomiRs Are Novel Components of Chronic TBI-Induced Neuropathology
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10010136
Abstract: Neuroinflammation is a secondary injury mechanism that evolves in the brain for months after traumatic brain injury (TBI). We hypothesized that an altered small non-coding RNA (sncRNA) signature plays a key role in modulating post-TBI… read more here.
Keywords: derived fragments; neuroinflammation; tbi; rna derived ... See more keywords
Small RNA Sequencing Reveals Transfer RNA-derived Small RNA Expression Profiles in Retinal Neovascularization
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.46209
Abstract: Retinal neovascularization (RNV) is characterized in retinopathy of prematurity (ROP), diabetic retinopathy (DR), and retinal vein occlusion (RVO), which leads to severe vision loss and even blindness. To reveal the altered transfer RNA-derived small RNA… read more here.
Keywords: small rna; rna derived; rna; transfer rna ... See more keywords