Comprehensive datasets for RNA design, machine learning, and beyond
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DOI: 10.1038/s41598-025-07041-2
Abstract: RNA molecules are essential in regulating biological processes such as gene expression, cellular differentiation, and development. Accurately predicting RNA secondary structures and designing sequences that fold into specific configurations remain significant challenges in computational biology,… read more here.
Keywords: rna design; biology; machine learning;
Evolutionary Strategy to Enhance an RNA Design Tool Performance
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DOI: 10.1109/access.2024.3358426
Abstract: At present, designing an RNA sequence that folds into a specific secondary structure is a problem that is not fully solved, due to its exponentially increasing complexity. To address this matter, many computational methods have… read more here.
Keywords: rna design; tool; rna; evolutionary strategy ... See more keywords
Fixed-parameter tractable sampling for RNA design with multiple target structures
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2784-7
Abstract: AbstractBackgroundThe design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the need for costly wet-lab experiments.ResultsWe devise a novel… read more here.
Keywords: rna design; multi; target; multiple target ... See more keywords