CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
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DOI: 10.1038/s41467-019-11759-9
Abstract: Transcription by RNA polymerase V (Pol V) in plants is required for RNA-directed DNA methylation, leading to transcriptional gene silencing. Global chromatin association of Pol V requires components of the DDR complex DRD1, DMS3 and… read more here.
Keywords: cryoem structures; dms3; dna methylation; rna directed ... See more keywords
Long-range control of gene expression via RNA-directed DNA methylation
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DOI: 10.1371/journal.pgen.1006749
Abstract: RNA-mediated transcriptional silencing, in plants known as RNA-directed DNA methylation (RdDM), is a conserved process where small interfering RNA (siRNA) and long non-coding RNA (lncRNA) help establish repressive chromatin modifications. This process represses transposons and… read more here.
Keywords: rna directed; rna; directed dna; rddm ... See more keywords
Analysis of Argonaute 4-Associated Long Non-Coding RNA in Arabidopsis thaliana Sheds Novel Insights into Gene Regulation through RNA-Directed DNA Methylation
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DOI: 10.3390/genes8080198
Abstract: RNA-directed DNA methylation (RdDM) is a plant-specific de novo DNA methylation mechanism that requires long noncoding RNA (lncRNA) as scaffold to define target genomic loci. While the role of RdDM in maintaining genome stability is… read more here.
Keywords: rna directed; gene; dna methylation; rddm ... See more keywords